Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia

Kinfe Fissehatsion; Ibrahim Ali; Ashebir Getachew

doi:doi:10.11648/j.ajhr.20170505.17

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Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia

Kinfe Fissehatsion, Ibrahim Ali, Ashebir Getachew

Published in American Journal of Health Research (Volume 5, Issue 5)

Received: 30 August 2017 Accepted: 13 September 2017 Published: 13 October 2017

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Abstract

Globally the burden of HIV, HBV and Syphilis infections are common problem of pregnant women where its complication isn’t only restricted to the pregnant women rather they are a serious issue for their newborn infants. Compared to developed country, developing countries including Ethiopia have been seriously influenced by such kinds of infections. Therefore this study have designed to determine the sero-prevalence and identify the possible risk factors of HIV, HBV and Syphilis infections in pregnant women providing health care services at Gandhi Memorial Hospital Addis Ababa, Ethiopia from January to April 2014. A Cross sectional study design has used and data on socio-demographic characteristics and possible risk factors have collected through pre-tested and structured questionnaire. After that blood have collected and screened for hepatitis B surface antigen using rapid cassette device and the final positive sample for HBsAg have confirmed by enzyme linked immunosorbent assay (ELISA). Antibodies to HIV-1/2 have tested based on the national testing algorism and Trepollema pallidum antibodies have tested by using Syphilis Rapid Test Strip (Quick Test™ Syphilis Serum/ Plasma/Whole Blood Strip). After the data have entered to Epi Info version 3.5.1 and exported to SPSS version 16 for validation and analysis, the overall prevalence of HIV-1/2 and HBsAg was 5.2%, 5% respectively while co-infection of HIV-HBV was 9.5% but no cases of Syphilis detected positive. In relation to the risk factors; history of sex with multiple sexual partners, pre-exposure to STI and low level of monthly income were significant risk factors for both HBV and HIV, while each infection found to have additional different risk factors; these includes: receiving of blood through donation, ear piercing and history of abortion for HBV infection while sharing different sharp materials and contact history with infected person for HIV infection alone. Therefore; intensified prevention activities in antenatal care targeting this population will have vital impact in halting the spread of the infections.

Published in	American Journal of Health Research (Volume 5, Issue 5)
DOI	10.11648/j.ajhr.20170505.17
Page(s)	154-161
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

HIV, HBsAg, Syphilis, Sero-prevalence, Risk Factors, Pregnant Women

References

[1]	Asaminew GMD. Primary HIV Infection in Patients Presenting with Conventional Sexually Transmitted Infections (STIs) in Ethiopia: Magnitude and Risk Factors [MSc Thesis]. Addis Ababa University, Ethiopia. 2006; 7-28.
[2]	Pan American Health Organization / World Health Organization (PAHO/WHO). Clinical Guideline for the Elimination of Mother-to-Child Transmission of HIV and Congenital Syphilis in Latin America and the Caribbean. Scientific publication. 2011; 9-90.
[3]	WHO. The Global HIV/AIDS Epidemic. 2013.
[4]	HAPCO. HIV/AIDS Estimates and Projections in Ethiopia, 2011-2016.
[5]	Federal Ministry of Heath/Ethiopian Health and Nutrition Research Institute. Report on the 2009 Round Antenatal Care Sentinel HIV Surveillance in Ethiopia, Addis Ababa, Ethiopia; 2011.
[6]	Feleke M, Yenew K, Afework K, Andargachew M, Moges T, Getu Detal. Seroprevalence of HIV, HBV infections and syphilis among street dwellers in Gonder city, North west Ethiopia. Ethiop. J. Health Dev. 2006; 20(3): 160-165.
[7]	Elsheikh RM, Daak AA, Mohamed A, Elsheikh MA, Karsany MS. Hepatitis B virus and hepatitis C virus in pregnant Sudanese women. Virol J. 2007; 4: 104-06.
[8]	Pungpapong S, Kim WR, Poterucha JJ. Natural History of HBV Infection: An Update for Clinicians. Mayo Clinical Procedures. 2007; 82: 967-975.
[9]	Ajayi B, Ajayi O, Hamidu I, Dawurung J, Ballah A, Isah Jet al. Seroprevalence of some sexually transmitted infections among antenatal attendees in university of Maiduguri teaching hospital, Maiduguri-Nigeria. Annals of Biological Research. 2013; 4 (2): 141-145.
[10]	Aron G, Laura B, Kelly C, Stephen K. Epidemiology of Sexually Transmitted Infections. Sex Trans Infect and Sex Transm Dis. 2011; 13-23.
[11]	Abdelbagi MN, Hager AW, Omer MK. Seroprevalence of Syphilis among pregnant Women in the Tri-capital, Khartoum, Sudan. Res. J. Medicine & Med. Sci. 2008; 3(1): 48-52.
[12]	Khayota Grace N. Prevalence of HSV-2, syphilis and HBV in HIV-1 individuals in selected health facilities in Nairobi, Kenya [MSc Thesis]. Kenyatta University, Kenya. 2012; 1-67.
[13]	Nicola M, Joseph E, Trevor P, Jeffrey D. Syphilis in the United States: An Update for Clinicians with an Emphasis on HIV Co-infection. Mayo Clin Proc. 2007; 82(9): 1091-1102.
[14]	Naing L, Winn T, Rusli BN. Practical Issues in Calculating the Sample Size for Prevalence Studies. Archives of Orofacial Sciences. 2006; 1: 9-14.
[15]	José M, Sofia B, Francisco R, Juan C, Gloria R, Félix G. Seroprevalence of HIV-1, HBV, HTLV-1 and T. pallidum infections among pregnant women in a rural hospital in Southern Ethiopia. Journal of clinical virology. 2011; 51(1): 83-85.
[16]	Henok S. Prevalence of HIV among antenatal care attendants at Kazanchis Health center in the last five years (2006-2010), Addis Ababa, Ethiopia. [MSc Thesis]. Addis Ababa University, Ethiopia. 2011; 1-38.
[17]	Mulu A, Kassu A, Tessema B,Yismaw G, Tiruneh M, Moges Fet al. Seroprevalence of syphilis and HIV-1 during pregnancy in a teaching hospital in Northwest Ethiopia. Jpn J Infect Dis. 2007; 60(4): 193-195.
[18]	Tiruneh M. Seroprevalence of multiple sexually transmitted infections among antenatal clinic attendees in Gonder Health Center, Northwest Ethiopia. Ethiop Med J. 2008; 46(4): 359-366.
[19]	Robert L, Silvia M, Lee H, Renaldo I, Roberta B, Sonia B et al. Prevalence of Sexually Transmitted Diseases in Young Women Seeking HIV Testing in Rio de Janeiro, Brazil. Sex Transm Dis. 2004; 31(1): 67–72.
[20]	Thu-Ha D, Mary L, Veerle M. Integration of Preventing Mother-To-Child Transmission of HIV and Syphilis Testing and Treatment in Antenatal Care Services in the Northern Cape and Gauteng Provinces, South Africa. Sex Transm Dis. 2013; 40(11): 846-850.
[21]	Yusuf K, Julius M, Raphael I, Julius M, Raphael I, John C et al. Trends in HIV & syphilis prevalence and correlates of HIV infection: results from cross-sectional surveys among women attending ante-natal clinics in Northern Tanzania. BMC Public Health. 2010; 10: 553.
[22]	Mbopi Kéou FX, Mbu R, Mauclère P,Andela A, Tetanye E, Léké Ret al. Antenatal HIV prevalence in Yaounde, Cameroon. Int J STD AIDS. 1998; 9(7): 400-4002.
[23]	Buseri F, Seiyaboh E, Jeremiah Z. Surveying Infections among Pregnant Women in Niger Delta, Nigeria. J Glob Infect Dis. 2010; 2(3): 203-211.
[24]	Christy NE, Denis E, Gilbert O,Chidi UI, Matthias I, Herbert O et al. The seroprevalence of HBsAg and HIV among pregnant women in Anambra state, Nigeria. Shiraz E-Medical Journal. 2004; 5(2): 1-8.
[25]	Bogaerts J, Ahmed J, Akhter N. sexually transmitted infections among married women in Dhaka, Bangladesh. Sex Transm Inf. 2001; 77: 114–119.
[26]	Yohannes Z, Wondemagegn M, Mulat Y and Bayeh A. Sero-prevalence and risk factors of hepatitis B virus and human immunodeficiency virus infection among pregnant women in Bahir Dar city, Northwest Ethiopia. BMC Infectious Diseases. 2014; 118(14): 1-7.
[27]	Juszozyk J: Clinical course and consequence of hepatitis B infection. Vaccine 2000, 18(Supp 1): S23–5.
[28]	Ndumbe PM, Skalsky J, Joller-Jemelka HI. Seroprevalence of HBV and HIV infection among rural pregnant women in Cameroon. APMIS. 1994; 102(9): 662-666.
[29]	Walle F, Asrat D, Alem A, Tadesse E, Desta K. Prevalence of HBsAg among pregnant women attending antenatal care service at Debre-tabor Hospital, Northwest Ethiopia. Ethiopia J Health Sci. 2008; 17(1): 13-21.
[30]	Angelica M, Marta CA, Regina LN, Kelly RA, Anto N. Seroprevalence of HIV, HBV and Syphilis in Women at Their First Visit to Public Antenatal Clinics, Brazil. Sex Transm Dis. 2001; 28(12): 710-713.
[31]	Gutiérrez ZN, Sánchez HJ, Muñoz S,Marin R, Delgado N, Saenz et al. Sero-prevalence of antibodies against Treponema pallidum, Toxoplasma gondii, rubella virus, HBV and HBC, and HIV in pregnant women. Enferm Infecc Microbiol Clin. 2004; 22(9): 512-6.
[32]	Jindal N, Arora U, Singh S, Devi B. Prevalence of Sexually Transmitted Infections (HIV, Hepatitis B, Herpes Simplex Type 2 and Syphilis) Among Asymptomatic Pregnant Women. J Obstet Gynecol India. 2012; 62(2): 158–161.
[33]	Awole M and Gebresilassie S. Seroprevalence of HBsAg and its risk factors among pregnant women in Jimma, Southwest Ethiopia. Ethiop. J. Health Dev. 2005; 19(1): 45-50.
[34]	José M, Sofia B, Francisco R, Juan C, Gloria R, Félix G. S eroprevalence of HIV-1, HBV, HTLV-1 and T. pallidum infections among pregnant women in a rural hospital in Southern Ethiopia. Journal of clinical virology. 2011; 51(1): 83-85.
[35]	Aidaoui M, Bouzbid S, Laouar M. Seroprevalence of HIV infection in pregnant women in the Annaba region, Algeria. Rev Epidemiol Sante Publique. 2008; 56(4): 261-6.
[36]	Mulu A, Kassu A, Tessema B,Yismaw G, Tiruneh M, Moges Fet al. Seroprevalence of syphilis and HIV-1 during pregnancy in a teaching hospital in Northwest Ethiopia. Jpn J Infect Dis. 2007; 60(4): 193-195.
[37]	Khayota Grace N. Prevalence of HSV-2, syphilis and HBV in HIV-1 individuals in selected health facilities in Nairobi, Kenya [MSc Thesis]. Kenyatta University, Kenya. 2012; 1-67.
[38]	Frank N, Okonko I, Okerentugba P, Jaja N. Detection of HIV1/2 Antibodies among Pregnant Women in Port Harcourt, Rivers State, Nigeria. World Appl. Sci. J. 2012; 16 (4): 589-598.
[39]	Shazia P, Shyamala R, Janardhan R, Rama Rao M. Sero-prevalence of HBsAg among pregnant women attending antenatal clinic in a teaching hospital. J. Microbiol. Biotech. Res. 2012; 2 (2): 343-345.
[40]	Elisabetta F, Barbara B, Maria G, Cristina M, Laura S, Laura Z. Hepatitis B: Epidemiology and prevention in developing countries. World J Hepatol. 2012; 4(3): 74-80.
[41]	Okonko I, Anugweje K,Adeniji F, Abdulyekeen R. Syphilis, HIV, HCV and HBsAg co-infections among Sexually Active Adults. Nature and Science. 2012; 10(1): 66-74.
[42]	Claire T, Ruslan M, Nina F, Irina E. Elimination of mother-to-child transmission of HIV in low-prevalence and concentrated epidemic settings in Eastern Europe and Central Asia. WHO. 2011; 13-80.
[43]	Satterwhite CL. Sexually transmitted infections among U.S. women and men: Prevalence and incidence estimates. Sex Transm Dis. 2013; 40(3): 187-193.
[44]	Sarwat F, Shirish V, Pavan KK. Seroprevalence of HIV, HBsAg, anti-HCV and syphilis in subjects attending integrated counseling and testing centre for HIV. AJMS. 2013; 6(4): 309-315.
[45]	Eticha BT, Sisay Z, Alemayehu A. Seroprevalence of syphilis among HIV-infected individuals in Addis Ababa, Ethiopia. BMJ. 2013; 1-7.

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APA Style

Kinfe Fissehatsion, Ibrahim Ali, Ashebir Getachew. (2017). Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia. American Journal of Health Research, 5(5), 154-161. https://doi.org/10.11648/j.ajhr.20170505.17

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ACS Style

Kinfe Fissehatsion; Ibrahim Ali; Ashebir Getachew. Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia. Am. J. Health Res. 2017, 5(5), 154-161. doi: 10.11648/j.ajhr.20170505.17

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AMA Style

Kinfe Fissehatsion, Ibrahim Ali, Ashebir Getachew. Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia. Am J Health Res. 2017;5(5):154-161. doi: 10.11648/j.ajhr.20170505.17

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@article{10.11648/j.ajhr.20170505.17,
  author = {Kinfe Fissehatsion and Ibrahim Ali and Ashebir Getachew},
  title = {Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia},
  journal = {American Journal of Health Research},
  volume = {5},
  number = {5},
  pages = {154-161},
  doi = {10.11648/j.ajhr.20170505.17},
  url = {https://doi.org/10.11648/j.ajhr.20170505.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20170505.17},
  abstract = {Globally the burden of HIV, HBV and Syphilis infections are common problem of pregnant women where its complication isn’t only restricted to the pregnant women rather they are a serious issue for their newborn infants. Compared to developed country, developing countries including Ethiopia have been seriously influenced by such kinds of infections. Therefore this study have designed to determine the sero-prevalence and identify the possible risk factors of HIV, HBV and Syphilis infections in pregnant women providing health care services at Gandhi Memorial Hospital Addis Ababa, Ethiopia from January to April 2014. A Cross sectional study design has used and data on socio-demographic characteristics and possible risk factors have collected through pre-tested and structured questionnaire. After that blood have collected and screened for hepatitis B surface antigen using rapid cassette device and the final positive sample for HBsAg have confirmed by enzyme linked immunosorbent assay (ELISA). Antibodies to HIV-1/2 have tested based on the national testing algorism and Trepollema pallidum antibodies have tested by using Syphilis Rapid Test Strip (Quick Test™ Syphilis Serum/ Plasma/Whole Blood Strip). After the data have entered to Epi Info version 3.5.1 and exported to SPSS version 16 for validation and analysis, the overall prevalence of HIV-1/2 and HBsAg was 5.2%, 5% respectively while co-infection of HIV-HBV was 9.5% but no cases of Syphilis detected positive. In relation to the risk factors; history of sex with multiple sexual partners, pre-exposure to STI and low level of monthly income were significant risk factors for both HBV and HIV, while each infection found to have additional different risk factors; these includes: receiving of blood through donation, ear piercing and history of abortion for HBV infection while sharing different sharp materials and contact history with infected person for HIV infection alone. Therefore; intensified prevention activities in antenatal care targeting this population will have vital impact in halting the spread of the infections.},
 year = {2017}
}

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TY  - JOUR
T1  - Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia
AU  - Kinfe Fissehatsion
AU  - Ibrahim Ali
AU  - Ashebir Getachew
Y1  - 2017/10/13
PY  - 2017
N1  - https://doi.org/10.11648/j.ajhr.20170505.17
DO  - 10.11648/j.ajhr.20170505.17
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
SP  - 154
EP  - 161
PB  - Science Publishing Group
SN  - 2330-8796
UR  - https://doi.org/10.11648/j.ajhr.20170505.17
AB  - Globally the burden of HIV, HBV and Syphilis infections are common problem of pregnant women where its complication isn’t only restricted to the pregnant women rather they are a serious issue for their newborn infants. Compared to developed country, developing countries including Ethiopia have been seriously influenced by such kinds of infections. Therefore this study have designed to determine the sero-prevalence and identify the possible risk factors of HIV, HBV and Syphilis infections in pregnant women providing health care services at Gandhi Memorial Hospital Addis Ababa, Ethiopia from January to April 2014. A Cross sectional study design has used and data on socio-demographic characteristics and possible risk factors have collected through pre-tested and structured questionnaire. After that blood have collected and screened for hepatitis B surface antigen using rapid cassette device and the final positive sample for HBsAg have confirmed by enzyme linked immunosorbent assay (ELISA). Antibodies to HIV-1/2 have tested based on the national testing algorism and Trepollema pallidum antibodies have tested by using Syphilis Rapid Test Strip (Quick Test™ Syphilis Serum/ Plasma/Whole Blood Strip). After the data have entered to Epi Info version 3.5.1 and exported to SPSS version 16 for validation and analysis, the overall prevalence of HIV-1/2 and HBsAg was 5.2%, 5% respectively while co-infection of HIV-HBV was 9.5% but no cases of Syphilis detected positive. In relation to the risk factors; history of sex with multiple sexual partners, pre-exposure to STI and low level of monthly income were significant risk factors for both HBV and HIV, while each infection found to have additional different risk factors; these includes: receiving of blood through donation, ear piercing and history of abortion for HBV infection while sharing different sharp materials and contact history with infected person for HIV infection alone. Therefore; intensified prevention activities in antenatal care targeting this population will have vital impact in halting the spread of the infections.
VL  - 5
IS  - 5
ER  -

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Author Information

Kinfe Fissehatsion

Department of Laboratory, Addis Ababa City Administration Health Bureau, Gandhi Memorial Hospital, Addis Ababa, Ethiopia
Ibrahim Ali

Department of Medical Laboratory Sciences, School of Allied Health Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Ashebir Getachew

Department of Obstetrics and Gynecology, Addis Ababa City Administration Health Bureau, Ghandi Memorial Hospital and Ethiopian Society of Obstetrics and Gynecology, Addis Ababa, Ethiopia

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APA Style

Kinfe Fissehatsion, Ibrahim Ali, Ashebir Getachew. (2017). Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia. American Journal of Health Research, 5(5), 154-161. https://doi.org/10.11648/j.ajhr.20170505.17

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ACS Style

Kinfe Fissehatsion; Ibrahim Ali; Ashebir Getachew. Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia. Am. J. Health Res. 2017, 5(5), 154-161. doi: 10.11648/j.ajhr.20170505.17

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AMA Style

Kinfe Fissehatsion, Ibrahim Ali, Ashebir Getachew. Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia. Am J Health Res. 2017;5(5):154-161. doi: 10.11648/j.ajhr.20170505.17

Copy | Download

@article{10.11648/j.ajhr.20170505.17,
  author = {Kinfe Fissehatsion and Ibrahim Ali and Ashebir Getachew},
  title = {Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia},
  journal = {American Journal of Health Research},
  volume = {5},
  number = {5},
  pages = {154-161},
  doi = {10.11648/j.ajhr.20170505.17},
  url = {https://doi.org/10.11648/j.ajhr.20170505.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20170505.17},
  abstract = {Globally the burden of HIV, HBV and Syphilis infections are common problem of pregnant women where its complication isn’t only restricted to the pregnant women rather they are a serious issue for their newborn infants. Compared to developed country, developing countries including Ethiopia have been seriously influenced by such kinds of infections. Therefore this study have designed to determine the sero-prevalence and identify the possible risk factors of HIV, HBV and Syphilis infections in pregnant women providing health care services at Gandhi Memorial Hospital Addis Ababa, Ethiopia from January to April 2014. A Cross sectional study design has used and data on socio-demographic characteristics and possible risk factors have collected through pre-tested and structured questionnaire. After that blood have collected and screened for hepatitis B surface antigen using rapid cassette device and the final positive sample for HBsAg have confirmed by enzyme linked immunosorbent assay (ELISA). Antibodies to HIV-1/2 have tested based on the national testing algorism and Trepollema pallidum antibodies have tested by using Syphilis Rapid Test Strip (Quick Test™ Syphilis Serum/ Plasma/Whole Blood Strip). After the data have entered to Epi Info version 3.5.1 and exported to SPSS version 16 for validation and analysis, the overall prevalence of HIV-1/2 and HBsAg was 5.2%, 5% respectively while co-infection of HIV-HBV was 9.5% but no cases of Syphilis detected positive. In relation to the risk factors; history of sex with multiple sexual partners, pre-exposure to STI and low level of monthly income were significant risk factors for both HBV and HIV, while each infection found to have additional different risk factors; these includes: receiving of blood through donation, ear piercing and history of abortion for HBV infection while sharing different sharp materials and contact history with infected person for HIV infection alone. Therefore; intensified prevention activities in antenatal care targeting this population will have vital impact in halting the spread of the infections.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Seroprevalence and Risk Factors of Sexually Transmitted Infections (HIV, HBV and Syphilis) Among Pregnant Women Provided Health Care Services, Addis Ababa, Ethiopia
AU  - Kinfe Fissehatsion
AU  - Ibrahim Ali
AU  - Ashebir Getachew
Y1  - 2017/10/13
PY  - 2017
N1  - https://doi.org/10.11648/j.ajhr.20170505.17
DO  - 10.11648/j.ajhr.20170505.17
T2  - American Journal of Health Research
JF  - American Journal of Health Research
JO  - American Journal of Health Research
SP  - 154
EP  - 161
PB  - Science Publishing Group
SN  - 2330-8796
UR  - https://doi.org/10.11648/j.ajhr.20170505.17
AB  - Globally the burden of HIV, HBV and Syphilis infections are common problem of pregnant women where its complication isn’t only restricted to the pregnant women rather they are a serious issue for their newborn infants. Compared to developed country, developing countries including Ethiopia have been seriously influenced by such kinds of infections. Therefore this study have designed to determine the sero-prevalence and identify the possible risk factors of HIV, HBV and Syphilis infections in pregnant women providing health care services at Gandhi Memorial Hospital Addis Ababa, Ethiopia from January to April 2014. A Cross sectional study design has used and data on socio-demographic characteristics and possible risk factors have collected through pre-tested and structured questionnaire. After that blood have collected and screened for hepatitis B surface antigen using rapid cassette device and the final positive sample for HBsAg have confirmed by enzyme linked immunosorbent assay (ELISA). Antibodies to HIV-1/2 have tested based on the national testing algorism and Trepollema pallidum antibodies have tested by using Syphilis Rapid Test Strip (Quick Test™ Syphilis Serum/ Plasma/Whole Blood Strip). After the data have entered to Epi Info version 3.5.1 and exported to SPSS version 16 for validation and analysis, the overall prevalence of HIV-1/2 and HBsAg was 5.2%, 5% respectively while co-infection of HIV-HBV was 9.5% but no cases of Syphilis detected positive. In relation to the risk factors; history of sex with multiple sexual partners, pre-exposure to STI and low level of monthly income were significant risk factors for both HBV and HIV, while each infection found to have additional different risk factors; these includes: receiving of blood through donation, ear piercing and history of abortion for HBV infection while sharing different sharp materials and contact history with infected person for HIV infection alone. Therefore; intensified prevention activities in antenatal care targeting this population will have vital impact in halting the spread of the infections.
VL  - 5
IS  - 5
ER  -

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