Information Loss in Transcribing Genetic Sequence from DNA into Protein

Alireza Sepehri; Somayyeh Shoorvazi

doi:doi:10.11648/j.bio.20130102.13

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Information Loss in Transcribing Genetic Sequence from DNA into Protein

Alireza Sepehri, Somayyeh Shoorvazi

Published in American Journal of Bioscience and Bioengineering (Volume 1, Issue 2)

Published: 2 April 2013

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Abstract

The main question is the probability of information loss in binding site of DNA due to interaction between DNA bead charges? Information loss in the gene expression disrupts the cellular dynamics and can lead to serious defects, including cancer. Using quantum biology ,a mechanism for calculating the amount of information loss in transcribing ge-netic sequence from DNA to protein is proposed. In this proposal, there are three different Hilbert spaces that belong to degrees of freedom of protein, binding site, and unbinding site of DNA. At first stage it is shown that the internal stationary state of the cell can be represented by a maximally entangled two-mode squeezed state of DNA and protein. At second stage,the state of the DNA is described by a maximally entangled two-mode squeezed state of DNA binding site and DNA unbinding site. Finally it is shown that the entanglement between protein and DNA is degraded due to interaction between DNA binding site and DNA unbinding site and consequently information is lost.

Published in	American Journal of Bioscience and Bioengineering (Volume 1, Issue 2)
DOI	10.11648/j.bio.20130102.13
Page(s)	31-35
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Gene Expression ,Unbinding Site, Information Loss

References

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[7]	Alfredo Iorio, Samik Sen, Siddhartha Sen, arXiv:0906.4015. Alfredo Iorio, Samik Sen, Siddhartha Sen, arXiv:0906.4015, arXiv:0806.3130
[8]	P.M. Alsing, I. Fuentes-Schuller,R.B. Mann, and T.E. Tessier. Phys. Rev. A, July 2006,arXiv:quant-ph/0603269.
[9]	D. Ahn, Y.H. Moon, R. B. Mann, I. Fuentes-Schuller, JHEP0806:062,2008
[10]	Alireza Sepehri, Somayyeh Shoorvazi. The Signature of Higgs Boson Near Surface Horizon of Oscillating Cylindrical Universe, American Journal of Modern Physics. Vol. 2, No. 3, 2013, pp. 124-131. doi: 10.11648/j.ajmp.20130203.15
[11]	Doyeol Ahn, Phys. Rev. D74: 084010, (2006).
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[13]	Alireza Sepehri , Somayyeh Shoorvazi. The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. American Journal of Bioscience and Bioengineering. Vol. 1, No. 2, 2013, pp. 38-42.doi: 10.11648/j.bio.20130102.12.

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Alireza Sepehri, Somayyeh Shoorvazi. (2013). Information Loss in Transcribing Genetic Sequence from DNA into Protein. American Journal of Bioscience and Bioengineering, 1(2), 31-35. https://doi.org/10.11648/j.bio.20130102.13

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ACS Style

Alireza Sepehri; Somayyeh Shoorvazi. Information Loss in Transcribing Genetic Sequence from DNA into Protein. Am. J. BioSci. Bioeng. 2013, 1(2), 31-35. doi: 10.11648/j.bio.20130102.13

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AMA Style

Alireza Sepehri, Somayyeh Shoorvazi. Information Loss in Transcribing Genetic Sequence from DNA into Protein. Am J BioSci Bioeng. 2013;1(2):31-35. doi: 10.11648/j.bio.20130102.13

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@article{10.11648/j.bio.20130102.13,
  author = {Alireza Sepehri and Somayyeh Shoorvazi},
  title = {Information Loss in Transcribing Genetic Sequence from DNA into Protein},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {1},
  number = {2},
  pages = {31-35},
  doi = {10.11648/j.bio.20130102.13},
  url = {https://doi.org/10.11648/j.bio.20130102.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20130102.13},
  abstract = {The main question is the probability of information loss in binding site of DNA due to interaction between DNA bead charges? Information loss in the gene expression disrupts the cellular dynamics and can lead to serious defects, including cancer. Using quantum biology ,a mechanism for calculating the amount of information loss in transcribing ge-netic sequence from DNA to protein is proposed. In this proposal, there are three different Hilbert spaces that belong to degrees of freedom of protein, binding site, and unbinding site of DNA. At first stage it is shown that the internal stationary state of the cell can be represented by a maximally entangled two-mode squeezed state of DNA and protein. At second stage,the state of the DNA is described by a maximally entangled two-mode squeezed state of DNA binding site and DNA unbinding site. Finally it is shown that the entanglement between protein and DNA is degraded due to interaction between DNA binding site and DNA unbinding site and consequently information is lost.},
 year = {2013}
}

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TY  - JOUR
T1  - Information Loss in Transcribing Genetic Sequence from DNA into Protein
AU  - Alireza Sepehri
AU  - Somayyeh Shoorvazi
Y1  - 2013/04/02
PY  - 2013
N1  - https://doi.org/10.11648/j.bio.20130102.13
DO  - 10.11648/j.bio.20130102.13
T2  - American Journal of Bioscience and Bioengineering
JF  - American Journal of Bioscience and Bioengineering
JO  - American Journal of Bioscience and Bioengineering
SP  - 31
EP  - 35
PB  - Science Publishing Group
SN  - 2328-5893
UR  - https://doi.org/10.11648/j.bio.20130102.13
AB  - The main question is the probability of information loss in binding site of DNA due to interaction between DNA bead charges? Information loss in the gene expression disrupts the cellular dynamics and can lead to serious defects, including cancer. Using quantum biology ,a mechanism for calculating the amount of information loss in transcribing ge-netic sequence from DNA to protein is proposed. In this proposal, there are three different Hilbert spaces that belong to degrees of freedom of protein, binding site, and unbinding site of DNA. At first stage it is shown that the internal stationary state of the cell can be represented by a maximally entangled two-mode squeezed state of DNA and protein. At second stage,the state of the DNA is described by a maximally entangled two-mode squeezed state of DNA binding site and DNA unbinding site. Finally it is shown that the entanglement between protein and DNA is degraded due to interaction between DNA binding site and DNA unbinding site and consequently information is lost.
VL  - 1
IS  - 2
ER  -

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Author Information

Alireza Sepehri

Faculty of Physics, Shahid Bahonar University, Kerman, Iran
Somayyeh Shoorvazi

Islamic Azad University, Neyshabur branch, Neyshabur, Iran

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APA Style

Alireza Sepehri, Somayyeh Shoorvazi. (2013). Information Loss in Transcribing Genetic Sequence from DNA into Protein. American Journal of Bioscience and Bioengineering, 1(2), 31-35. https://doi.org/10.11648/j.bio.20130102.13

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ACS Style

Alireza Sepehri; Somayyeh Shoorvazi. Information Loss in Transcribing Genetic Sequence from DNA into Protein. Am. J. BioSci. Bioeng. 2013, 1(2), 31-35. doi: 10.11648/j.bio.20130102.13

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AMA Style

Alireza Sepehri, Somayyeh Shoorvazi. Information Loss in Transcribing Genetic Sequence from DNA into Protein. Am J BioSci Bioeng. 2013;1(2):31-35. doi: 10.11648/j.bio.20130102.13

Copy | Download

@article{10.11648/j.bio.20130102.13,
  author = {Alireza Sepehri and Somayyeh Shoorvazi},
  title = {Information Loss in Transcribing Genetic Sequence from DNA into Protein},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {1},
  number = {2},
  pages = {31-35},
  doi = {10.11648/j.bio.20130102.13},
  url = {https://doi.org/10.11648/j.bio.20130102.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20130102.13},
  abstract = {The main question is the probability of information loss in binding site of DNA due to interaction between DNA bead charges? Information loss in the gene expression disrupts the cellular dynamics and can lead to serious defects, including cancer. Using quantum biology ,a mechanism for calculating the amount of information loss in transcribing ge-netic sequence from DNA to protein is proposed. In this proposal, there are three different Hilbert spaces that belong to degrees of freedom of protein, binding site, and unbinding site of DNA. At first stage it is shown that the internal stationary state of the cell can be represented by a maximally entangled two-mode squeezed state of DNA and protein. At second stage,the state of the DNA is described by a maximally entangled two-mode squeezed state of DNA binding site and DNA unbinding site. Finally it is shown that the entanglement between protein and DNA is degraded due to interaction between DNA binding site and DNA unbinding site and consequently information is lost.},
 year = {2013}
}

Copy | Download

TY  - JOUR
T1  - Information Loss in Transcribing Genetic Sequence from DNA into Protein
AU  - Alireza Sepehri
AU  - Somayyeh Shoorvazi
Y1  - 2013/04/02
PY  - 2013
N1  - https://doi.org/10.11648/j.bio.20130102.13
DO  - 10.11648/j.bio.20130102.13
T2  - American Journal of Bioscience and Bioengineering
JF  - American Journal of Bioscience and Bioengineering
JO  - American Journal of Bioscience and Bioengineering
SP  - 31
EP  - 35
PB  - Science Publishing Group
SN  - 2328-5893
UR  - https://doi.org/10.11648/j.bio.20130102.13
AB  - The main question is the probability of information loss in binding site of DNA due to interaction between DNA bead charges? Information loss in the gene expression disrupts the cellular dynamics and can lead to serious defects, including cancer. Using quantum biology ,a mechanism for calculating the amount of information loss in transcribing ge-netic sequence from DNA to protein is proposed. In this proposal, there are three different Hilbert spaces that belong to degrees of freedom of protein, binding site, and unbinding site of DNA. At first stage it is shown that the internal stationary state of the cell can be represented by a maximally entangled two-mode squeezed state of DNA and protein. At second stage,the state of the DNA is described by a maximally entangled two-mode squeezed state of DNA binding site and DNA unbinding site. Finally it is shown that the entanglement between protein and DNA is degraded due to interaction between DNA binding site and DNA unbinding site and consequently information is lost.
VL  - 1
IS  - 2
ER  -

Copy | Download