Background. Energy balance in blood and body may differ for a day or two although compensating in a month. Most people (60%) maintain a positive energy balance and a high blood glucose (BG) high energy availability in blood and high resting metabolic rate that correspond to insulin resistance/fattening and ill health. A meal/satiety pattern dictated by the rhythmic arousal of Initial Hunger (IH and IHMP) improved exhaustion of the energy consumed in previous meals and decreased high energy intake, high preprandial BG, high resting metabolic rate (RMR), insulin resistance, overall subclinical inflammation, vascular risks, deteriorations and functional disorders. Methods. We defined Initial Hunger as sensations that spontaneously arise after eating suspension. IH consistently arouse in different groups when BG declined toward 76.6 ± 3.7 mg/dL. A week diary reported assessments of IH and preprandial BG measurements before the three main meals. Mean BG in a week was stratified within normal BG limits, but different subjects pertained to different strata. Thirty-one untrained control adults maintained his/her own mean and BG stratum for five months. After training, these subjects changed his/her own mean BG to the stratum that was associated with IHMP. Measurements reported by diary, of RMR and of total energy expenditure demonstrated this stratum change. From recruitment, the mean decrease was 15.4% by indirect calorimetry and 15.5% by doubly labeled water in a total of 24 toddlers (P < 0.001). Mean BG thus assessed the deviation of a meal pattern from the mean BG associated with IH (IHMP). Results. In San Diego ASN 2014, we showed the effectiveness of IHMP on regression of fattening/insulin resistance for a long term in 181 adults of mixed body weight who had bowel functional disorders and were clinically normal. However we had earlier designed IHMP for a broader aim as compared to a body loss device. We wanted to educate children and future adults to an intestinal low immune involvement and to the best fitting of intake to body regulations. Thus, we tried to publish the recovery of diarrheic malnourished infants by IHMP in an American Society for Nutrition (ASN) Journal. Subjects were aged less than 15 months, had lower body weight per age than 70% and recovered through many months and years. This aim was right opposite to weight loss. The ASN Journal rejected the publication as findings of clinical but no nutritional interest. Med Crave promptly published the findings. In a broader thought, the ASN Journal protected the established assistance beliefs and trusts from the confounding intrusion of an innovative, self-help system (IHMP).
| Published in | International Journal of Nutrition and Food Sciences (Volume 3, Issue 4) |
| DOI | 10.11648/j.ijnfs.20140304.20 |
| Page(s) | 300-306 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Energy Balance, Meal Energy Load, Malnutrition, Overweight, Immune Improvement
| [1] | Ciampolini M, Vicarelli D, Seminara S. Normal energy intake range in children with chronic non-specific diarrhea. Association of relapses with the higher level. J Pediatr Gastroenter Nutr 1990; 11: 342-50. |
| [2] | Ciampolini M, Vicarelli D, Bini S. Choices at weaning, main factor of ingestive behavior. Nutrition 1991; 7: 51-54. |
| [3] | Ciampolini M, Bini S, Giommi A, Vicarelli D, Giannellini V. Same growth and different energy intake in chronic non-specific diarrhea children in a four-year period. Intern J Obesity 1994; 18: 17-23. |
| [4] | Ciampolini M, Borselli L, Giannellini V . Attention to metabolic hunger and its effects on Helicobacter pylori infection. Physiol Behav 2000; 70: 287-296. |
| [5] |
Ciampolini M, Lovell-Smith D, Sifone M: Sustained self-regulation of energy intake. Loss of weight in overweight subjects. Maintenance of weight in normal-weight subjects. Nutr Metab (Lond). 2010;7:1–4. |
| [6] |
Ciampolini M, Sifone M. Differences in maintenance of mean Blood glucose (BG) and their association with response to “Recognizing Hunger”. I J Gen Med 2011, 4, 403-412. |
| [7] | Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world – a growing challenge. N Engl J Med. 2007;356(3):213–215. |
| [8] | Mozaffarian D, Hao T, Rimm EB, Willett WC, Hu FB. Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med. 2011;364(25):2392–2404. |
| [9] | Sumithran P, Prendergast LA, Delbridge E, et al. Long-term persistence of hormonal adaptations to weight loss. N Engl J Med. 2011; 365(17):1597–1604. |
| [10] |
Ciampolini M. Initial hunger and exhaustion of previous energy intake- Recognizing hunger, and energy balance (Rev Recent. Res. Devel. Nutrition, 8 (2011): ISBN: 978-81-308-0468-2 |
| [11] |
Ciampolini M. Eliciting Clear-Cut Initial-Hunger at Proper Time. OMICS Publishing Group 2012: |
| [12] |
Ciampolini M, Editor. Meal by meal dynamic balance of energy in blood. Research Signpost, 37/661(2), Vazhappalli Jn., Fort Post Office, Trivandrum-695 023, Kerala, INDIA. ISBN: 978-81-308-0457-6 |
| [13] | Gavin JR: Pathophysiologic mechanisms of postprandial hyperglycemia. Am J Cardiol 2001, 88:S4-S8. |
| [14] | de Graaf C, Blom WAM, Smeets PAM, Stafleu A, Hendriks HFJ:Biomarkers of satiation and satiety. Am J Clin Nutr 2004,79:946-961. |
| [15] | 10 Elliott SS, Keim NL, Stern JS, Teff K, Havel PJ: Fructose, weight gain, and the insulin resistance syndrome. Am J Clin Nutr 2002,76:911-922. |
| [16] |
Ciampolini M, Lovell-Smith D, Bianchi R, de Pont B, Sifone M, van Weeren M, de Hahn W, Borselli L, Pietrobelli A. Sustained self-regulation of energy intake. Initial hunger improves insulin sensitivity. J Nutr Metab 2010, Article ID 286952, 7 pages. doi:10.1155/2010/286952 |
| [17] |
Ciampolini M, Bianchi R: Training to estimate blood glucose and to form associations with initial hunger. Nutr Metab (Lond). 2006; 3:42. |
| [18] |
Ciampolini M. Requested meals versus scheduled meals. I J Gen Med 2012:5 1–9. DOI: doi.org/10.2147/IJGM.S29889 |
| [19] |
Ciampolini M, Brenna JT, Giannellini V, Bini S. Interruption of scheduled, automatic feeding and reduction of excess energy intake in toddlers. Intern J Gen Med 2013, |
| [20] | Selvin E, Steffes MW, Zhu H, Matsushita K, Wagenknecht L, Pankow J, Coresh J, Brancati FL. Cardiovascular Risk in Nondiabetic Adults. N Engl J Med 2010;362:800-11. |
| [21] | Brandtzaeg P, Halstensen T S, Kett K, Krajci P, Kvale D, Rognum TO, Scott H, Sollid LM. Immunobiology and immunopathology of human gut mucosa: humoral immunity and intreaepithelial lymphocytes. Gastroenterology 1989; 97:1562-1584. |
| [22] | Abrams GD. Microbial effects on mucosal structure and function. Am J Clin Nutr 1977;30:1880-1886. |
| [23] | Kinugasa T, Sakaguchi T, Gu X, Reinecker HC. Claudins regulate the intestinal barrier in response to immune mediators. Gastroenterology 2000; 118: 1001-1011. |
| [24] | Perez PF, Doré J, Leclerc M, Levenez F, Benyacoub J, Serrant P, Segura-Roggero I, Schiffrin EJ, Donnet-Hughes A. Bacterial Imprinting of the Neonatal Immune System: Lessons From Maternal Cells? Pediatrics 2007; 119: e724-e732. |
| [25] | Smith CW. Diet and leukocytes. Am J Clin Nutr 2007; 86: 1257-1258. |
| [26] | Reaven GM: The metabolic syndrome: is this diagnosis necessary? Am J Clin Nutr 2006; 83:1237-1247. |
| [27] | Reaven, G.M. Role of insulin resistance in human disease. Banting Lecture 1988. Diabetes 1988;37: 1595-1607;. |
| [28] | Wilson KT,. Crabtree JE. Immunology of Helicobacter pylori: Insights Into the Failure of the Immune Response and Perspectives on Vaccine Studies. Gastroenterology 2005; 129: 380-383 |
| [29] | Hecht G. In the Beginning Was Helicobacter pylori: Roles for Microbes in Other Intestinal Disorders. Gastroenterology 2007; 132: 481-483. |
| [30] | Abraham C, Cho JH. Inflammatory bowel disease. N Engl J Med 2009; 361:2066-2078. |
| [31] | Sartor B: Microbial influences in Inflammatory Bowel Disease. Gastroenterology 2008; 134:577-594. |
| [32] | Davidson GP, Robb TA, Kirubakaran CP. Bacterial contamination of the small intestine as an important cause of chronic diarrhea and abdominal pain: diagnosis by breath hydrogen test. Pediatrics 1984;74:229-235. |
| [33] | Azpiroz F, Bouin M, Camilleri M, et al. Mechanisms of hypersensitivity in IBS and functional disorders. Neurogastroenterol Motil. Jan 2007;19(1 Suppl):62-88. |
| [34] | van der Waaij LA, Limburg PC, Mesander G, van der Waaij, D. In vivo IgA coating of anaerobic bacteria in human faeces. Gut 1996;38:348-354 |
| [35] | Dinan TG, Quigley EM, Ahmed SM, Scully P, O’Brien S, O’Mahony L., O’Mahony S, Shanahan F, Keeling N. Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? Gastroenterology 2006;130:304-311. |
| [36] | Ohman L, Simrén M. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat Rev Gastroenterol Hepatol 2010; 7(3):163-173. |
| [37] | Spiller R, Garsed K. Postinfectious irritable bowel syndrome. Gastroenterology 2009;136(6):1979-1988. |
| [38] | Li X, Chen H, Lu H, Li W, Chen X, Peng Y, Ge Z. The study on the role of inflammatory cells and mediators in post-infectious functional dyspepsia. Scand. J Gastroenterol 2010;45(5):573-581. Sartor B. Microbial influences in Inflammatory Bowel Disease. Gastroenterology 2008; 134:577-594. |
| [39] | Ciampolini M, Bini S. Orsi A. Microflora persistence on duodeno-jejunal flat or normal mucosa in time after a meal in children. Physiol Behav 1996; 60: 1551-1556. |
| [40] | Brunser O, Eidelman S, Klipstein FA. Intestinal morphology of rural Haitians. A comparison between overt tropical sprue and asymptomatic subjects. Gastroenterology 1970; 58:655-668. |
| [41] | Gorbach SL, Banwell JG, Chatterjee BD, Jacobs B, Sack RB. Acute, undifferentiated human diarrhea in the tropics. I Alterations in intestinal microflora. J Clin Invest 1971; 50:881-889. |
| [42] | Terziæ, J, Grivennikov, S, Karin, E, Karin, M. Inflammation and Colon Cancer. Gastroenterology 2010:138:2101-2114. |
| [43] | Liebregts T, Adam B, Bredack C, Röth A, Heinzel S, Lester S, Downie-Doyle S, Smith E, Drew P, Talley NJ, Holtman G. Immune Activation in Patients With Irritable Bowel Syndrome. Gastroenterology 2006; 132: 913-920. |
| [44] | Ciampolini M, Bianchi R, Sifone M., Riccardo Bianchi and Massimiliano Sifone “Initial Hunger” for All? A Study on Undernourished Infants. Journal of Pediatrics & Neonatal Care. Volume 1 Issue 2 – 2014. |
| [45] | Feyerabend P. Philosophy, chapter 9, Biddles Ltd, Guilford, GB, 1987. |
| [46] | Kylin E. Studien ueber Hypertonie-Hyperglykamie-Hyperurikamie syndrome. 1923, Zentralblatt fur innere Medizin, 44. |
| [47] | Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose-fatty acid cycle: its role in insulin sensityvity and the metabolic disturbances of diabetes mellitus. Lancet 1963;93:785-789. |
APA Style
Mario Ciampolini. (2014). New Findings on Energy Balance and Established Wisdom. International Journal of Nutrition and Food Sciences, 3(4), 300-306. https://doi.org/10.11648/j.ijnfs.20140304.20
ACS Style
Mario Ciampolini. New Findings on Energy Balance and Established Wisdom. Int. J. Nutr. Food Sci. 2014, 3(4), 300-306. doi: 10.11648/j.ijnfs.20140304.20
AMA Style
Mario Ciampolini. New Findings on Energy Balance and Established Wisdom. Int J Nutr Food Sci. 2014;3(4):300-306. doi: 10.11648/j.ijnfs.20140304.20
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Download@article{10.11648/j.ijnfs.20140304.20,
author = {Mario Ciampolini},
title = {New Findings on Energy Balance and Established Wisdom},
journal = {International Journal of Nutrition and Food Sciences},
volume = {3},
number = {4},
pages = {300-306},
doi = {10.11648/j.ijnfs.20140304.20},
url = {https://doi.org/10.11648/j.ijnfs.20140304.20},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20140304.20},
abstract = {Background. Energy balance in blood and body may differ for a day or two although compensating in a month. Most people (60%) maintain a positive energy balance and a high blood glucose (BG) high energy availability in blood and high resting metabolic rate that correspond to insulin resistance/fattening and ill health. A meal/satiety pattern dictated by the rhythmic arousal of Initial Hunger (IH and IHMP) improved exhaustion of the energy consumed in previous meals and decreased high energy intake, high preprandial BG, high resting metabolic rate (RMR), insulin resistance, overall subclinical inflammation, vascular risks, deteriorations and functional disorders. Methods. We defined Initial Hunger as sensations that spontaneously arise after eating suspension. IH consistently arouse in different groups when BG declined toward 76.6 ± 3.7 mg/dL. A week diary reported assessments of IH and preprandial BG measurements before the three main meals. Mean BG in a week was stratified within normal BG limits, but different subjects pertained to different strata. Thirty-one untrained control adults maintained his/her own mean and BG stratum for five months. After training, these subjects changed his/her own mean BG to the stratum that was associated with IHMP. Measurements reported by diary, of RMR and of total energy expenditure demonstrated this stratum change. From recruitment, the mean decrease was 15.4% by indirect calorimetry and 15.5% by doubly labeled water in a total of 24 toddlers (P < 0.001). Mean BG thus assessed the deviation of a meal pattern from the mean BG associated with IH (IHMP). Results. In San Diego ASN 2014, we showed the effectiveness of IHMP on regression of fattening/insulin resistance for a long term in 181 adults of mixed body weight who had bowel functional disorders and were clinically normal. However we had earlier designed IHMP for a broader aim as compared to a body loss device. We wanted to educate children and future adults to an intestinal low immune involvement and to the best fitting of intake to body regulations. Thus, we tried to publish the recovery of diarrheic malnourished infants by IHMP in an American Society for Nutrition (ASN) Journal. Subjects were aged less than 15 months, had lower body weight per age than 70% and recovered through many months and years. This aim was right opposite to weight loss. The ASN Journal rejected the publication as findings of clinical but no nutritional interest. Med Crave promptly published the findings. In a broader thought, the ASN Journal protected the established assistance beliefs and trusts from the confounding intrusion of an innovative, self-help system (IHMP).},
year = {2014}
}
TY - JOUR T1 - New Findings on Energy Balance and Established Wisdom AU - Mario Ciampolini Y1 - 2014/07/20 PY - 2014 N1 - https://doi.org/10.11648/j.ijnfs.20140304.20 DO - 10.11648/j.ijnfs.20140304.20 T2 - International Journal of Nutrition and Food Sciences JF - International Journal of Nutrition and Food Sciences JO - International Journal of Nutrition and Food Sciences SP - 300 EP - 306 PB - Science Publishing Group SN - 2327-2716 UR - https://doi.org/10.11648/j.ijnfs.20140304.20 AB - Background. Energy balance in blood and body may differ for a day or two although compensating in a month. Most people (60%) maintain a positive energy balance and a high blood glucose (BG) high energy availability in blood and high resting metabolic rate that correspond to insulin resistance/fattening and ill health. A meal/satiety pattern dictated by the rhythmic arousal of Initial Hunger (IH and IHMP) improved exhaustion of the energy consumed in previous meals and decreased high energy intake, high preprandial BG, high resting metabolic rate (RMR), insulin resistance, overall subclinical inflammation, vascular risks, deteriorations and functional disorders. Methods. We defined Initial Hunger as sensations that spontaneously arise after eating suspension. IH consistently arouse in different groups when BG declined toward 76.6 ± 3.7 mg/dL. A week diary reported assessments of IH and preprandial BG measurements before the three main meals. Mean BG in a week was stratified within normal BG limits, but different subjects pertained to different strata. Thirty-one untrained control adults maintained his/her own mean and BG stratum for five months. After training, these subjects changed his/her own mean BG to the stratum that was associated with IHMP. Measurements reported by diary, of RMR and of total energy expenditure demonstrated this stratum change. From recruitment, the mean decrease was 15.4% by indirect calorimetry and 15.5% by doubly labeled water in a total of 24 toddlers (P < 0.001). Mean BG thus assessed the deviation of a meal pattern from the mean BG associated with IH (IHMP). Results. In San Diego ASN 2014, we showed the effectiveness of IHMP on regression of fattening/insulin resistance for a long term in 181 adults of mixed body weight who had bowel functional disorders and were clinically normal. However we had earlier designed IHMP for a broader aim as compared to a body loss device. We wanted to educate children and future adults to an intestinal low immune involvement and to the best fitting of intake to body regulations. Thus, we tried to publish the recovery of diarrheic malnourished infants by IHMP in an American Society for Nutrition (ASN) Journal. Subjects were aged less than 15 months, had lower body weight per age than 70% and recovered through many months and years. This aim was right opposite to weight loss. The ASN Journal rejected the publication as findings of clinical but no nutritional interest. Med Crave promptly published the findings. In a broader thought, the ASN Journal protected the established assistance beliefs and trusts from the confounding intrusion of an innovative, self-help system (IHMP). VL - 3 IS - 4 ER -
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