The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules

Bi Xiaodong; Ma Jingmei; Tian Wei; Peng Xinhua; Gao Han; Li Junshan; Niu Liying

doi:doi:10.11648/j.mc.20180602.11

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The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules

Bi Xiaodong, Ma Jingmei, Tian Wei, Peng Xinhua, Gao Han, Li Junshan, Niu Liying

Published in Modern Chemistry (Volume 6, Issue 2)

Received: 13 June 2018 Accepted: 28 June 2018 Published: 23 July 2018

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Abstract

Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.

Published in	Modern Chemistry (Volume 6, Issue 2)
DOI	10.11648/j.mc.20180602.11
Page(s)	15-19
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Formula Granule, Danggui, IR, Lab Environment, Discrimination

References

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APA Style

Bi Xiaodong, Ma Jingmei, Tian Wei, Peng Xinhua, Gao Han, et al. (2018). The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Modern Chemistry, 6(2), 15-19. https://doi.org/10.11648/j.mc.20180602.11

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ACS Style

Bi Xiaodong; Ma Jingmei; Tian Wei; Peng Xinhua; Gao Han, et al. The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Mod. Chem. 2018, 6(2), 15-19. doi: 10.11648/j.mc.20180602.11

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AMA Style

Bi Xiaodong, Ma Jingmei, Tian Wei, Peng Xinhua, Gao Han, et al. The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Mod Chem. 2018;6(2):15-19. doi: 10.11648/j.mc.20180602.11

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@article{10.11648/j.mc.20180602.11,
  author = {Bi Xiaodong and Ma Jingmei and Tian Wei and Peng Xinhua and Gao Han and Li Junshan and Niu Liying},
  title = {The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules},
  journal = {Modern Chemistry},
  volume = {6},
  number = {2},
  pages = {15-19},
  doi = {10.11648/j.mc.20180602.11},
  url = {https://doi.org/10.11648/j.mc.20180602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.mc.20180602.11},
  abstract = {Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.},
 year = {2018}
}

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TY  - JOUR
T1  - The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules
AU  - Bi Xiaodong
AU  - Ma Jingmei
AU  - Tian Wei
AU  - Peng Xinhua
AU  - Gao Han
AU  - Li Junshan
AU  - Niu Liying
Y1  - 2018/07/23
PY  - 2018
N1  - https://doi.org/10.11648/j.mc.20180602.11
DO  - 10.11648/j.mc.20180602.11
T2  - Modern Chemistry
JF  - Modern Chemistry
JO  - Modern Chemistry
SP  - 15
EP  - 19
PB  - Science Publishing Group
SN  - 2329-180X
UR  - https://doi.org/10.11648/j.mc.20180602.11
AB  - Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.
VL  - 6
IS  - 2
ER  -

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Author Information

Bi Xiaodong

Department of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, China
Ma Jingmei

Department of Laboratory Center, Hebei University of Chinese Medicine, Shijiazhuang, China
Tian Wei

Department of Laboratory Center, Hebei University of Chinese Medicine, Shijiazhuang, China
Peng Xinhua

Shineway Pharmaceutical Group Ltd, Shijiazhuang, China
Gao Han

Shineway Pharmaceutical Group Ltd, Shijiazhuang, China
Li Junshan

Shineway Pharmaceutical Group Ltd, Shijiazhuang, China
Niu Liying

Department of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, China

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Plain Text BibTeX RIS

APA Style

Bi Xiaodong, Ma Jingmei, Tian Wei, Peng Xinhua, Gao Han, et al. (2018). The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Modern Chemistry, 6(2), 15-19. https://doi.org/10.11648/j.mc.20180602.11

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ACS Style

Bi Xiaodong; Ma Jingmei; Tian Wei; Peng Xinhua; Gao Han, et al. The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Mod. Chem. 2018, 6(2), 15-19. doi: 10.11648/j.mc.20180602.11

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AMA Style

Bi Xiaodong, Ma Jingmei, Tian Wei, Peng Xinhua, Gao Han, et al. The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Mod Chem. 2018;6(2):15-19. doi: 10.11648/j.mc.20180602.11

Copy | Download

@article{10.11648/j.mc.20180602.11,
  author = {Bi Xiaodong and Ma Jingmei and Tian Wei and Peng Xinhua and Gao Han and Li Junshan and Niu Liying},
  title = {The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules},
  journal = {Modern Chemistry},
  volume = {6},
  number = {2},
  pages = {15-19},
  doi = {10.11648/j.mc.20180602.11},
  url = {https://doi.org/10.11648/j.mc.20180602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.mc.20180602.11},
  abstract = {Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules
AU  - Bi Xiaodong
AU  - Ma Jingmei
AU  - Tian Wei
AU  - Peng Xinhua
AU  - Gao Han
AU  - Li Junshan
AU  - Niu Liying
Y1  - 2018/07/23
PY  - 2018
N1  - https://doi.org/10.11648/j.mc.20180602.11
DO  - 10.11648/j.mc.20180602.11
T2  - Modern Chemistry
JF  - Modern Chemistry
JO  - Modern Chemistry
SP  - 15
EP  - 19
PB  - Science Publishing Group
SN  - 2329-180X
UR  - https://doi.org/10.11648/j.mc.20180602.11
AB  - Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.
VL  - 6
IS  - 2
ER  -

Copy | Download