The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe

Alireza Sepehri; Somayyeh Shoorvazi

doi:doi:10.11648/j.bio.20130102.12

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The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe

Alireza Sepehri, Somayyeh Shoorvazi

Published in American Journal of Bioscience and Bioengineering (Volume 1, Issue 2)

Published: 2 April 2013

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Abstract

One of the most exciting subjects in science is the possibility of information loss in transcribing genetic se-quence of DNA into proteins due to acceleration of Universe. This research is the first attempt to investigate this subject. First, the probability that DNA is produced due to acceleration of Universe is obtained. It is found that as the Unruh tem-perature increases, the effect ofacceleration on the production of DNA becomes systematically more effective, because effect at higher temperatures, the energy that is supplied to keep Universe undergoing acceleration becomes more and consequently more DNAs are produced. Then the average number of binding proteins to DNA in two regions of Rindler space of Universe is calculated. The effect of proteins produced in region II doesn’t observe in accelerating Universe. One observer in acceleratingUniverse is unable to access information about the whole of space-time since, from his perspective, a communication horizon appears. This can result in a loss of information and a corresponding degradation ofprotein binding to DNA. This information loss disrupts the cellular dynamics and can lead to serious defects, including cancer.Next the averge number of extra base pairs that are produced in DNA structure by the acceleration of Universe is derived. These extra base pairs cause to be stored more information in DNA.These information can be transcribed of DNA into proteins and lead to dangerous activity in Human body.Finally,the probability for substituting AT pair by CG pair in DNA structure is calculated. It’s concluded that with increasing the Unruh temperature, more AT base pairs may be substituted by CG pairs and the probability for generating cancer due to this point mutation is increased.

Published in	American Journal of Bioscience and Bioengineering (Volume 1, Issue 2)
DOI	10.11648/j.bio.20130102.12
Page(s)	38-42
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Acceleration Of Universe, DNA , Information Loss

References

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[2]	D. N. Spergel et al.,Astrophys. J. Suppl. 148, 175 (2003)
[3]	I. Fuentes-Schuller and R. B. Mann, Phys. Rev. Lett. 95, 120404 (2005).
[4]	P. M. Alsing, I. Fuentes-Schuller, R. B. Mann, and T. E. Tessier, Phys. Rev.A74, 032326 (2006).
[5]	Michel Peyrard, Santiago Cuesta-Lopez, Dimitar Angelov , Journal of Physics: Condensed Matter 3, 21 (2008) 034103-1-13
[6]	Branko Dragovich, Alexandra Dragovich, p-Adic Num-bers,Ultrametric Analysis and Applications 1 (2009) 34-41
[7]	Jose M. G. Vilar and Leonor Saiz,Phys. Rev. Lett. 96, 238103 (2006)
[8]	C. J. Sherr, Cell 234, 116 (2004).
[9]	A. Petitjean et al., Hum. Mutat. 28, 622 (2007), Chi-Tin Shih, Stephan Roche, Rudolf A. Römer, Phys. Rev. Lett. 100,018105 (2008)

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Alireza Sepehri, Somayyeh Shoorvazi. (2013). The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. American Journal of Bioscience and Bioengineering, 1(2), 38-42. https://doi.org/10.11648/j.bio.20130102.12

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ACS Style

Alireza Sepehri; Somayyeh Shoorvazi. The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. Am. J. BioSci. Bioeng. 2013, 1(2), 38-42. doi: 10.11648/j.bio.20130102.12

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AMA Style

Alireza Sepehri, Somayyeh Shoorvazi. The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. Am J BioSci Bioeng. 2013;1(2):38-42. doi: 10.11648/j.bio.20130102.12

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@article{10.11648/j.bio.20130102.12,
  author = {Alireza Sepehri and Somayyeh Shoorvazi},
  title = {The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {1},
  number = {2},
  pages = {38-42},
  doi = {10.11648/j.bio.20130102.12},
  url = {https://doi.org/10.11648/j.bio.20130102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20130102.12},
  abstract = {One of the most exciting subjects in science is the possibility of information loss in transcribing genetic se-quence of DNA into proteins due to acceleration of Universe. This research is the first attempt to investigate this subject. First, the probability that DNA is produced due to acceleration of Universe is obtained. It is found that as the Unruh tem-perature increases, the effect ofacceleration on the production of DNA becomes systematically more effective, because effect at higher temperatures, the energy that is supplied to keep Universe undergoing acceleration becomes more and consequently more DNAs are produced. Then the average number of binding proteins to DNA in two regions of Rindler space of Universe is calculated. The effect of proteins produced in region II doesn’t observe in accelerating Universe. One observer in acceleratingUniverse is unable to access information about the whole of space-time since, from his perspective, a communication horizon appears. This can result in a loss of information and a corresponding degradation ofprotein binding to DNA. This information loss disrupts the cellular dynamics and can lead to serious defects, including cancer.Next the averge number of extra base pairs that are produced in DNA structure by the acceleration of Universe is derived. These extra base pairs cause to be stored more information in DNA.These information can be transcribed of DNA into proteins and lead to dangerous activity in Human body.Finally,the probability for substituting AT pair by CG pair in DNA structure is calculated. It’s concluded that with increasing the Unruh temperature, more AT base pairs may be substituted by CG pairs and the probability for generating cancer due to this point mutation is increased.},
 year = {2013}
}

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TY  - JOUR
T1  - The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe
AU  - Alireza Sepehri
AU  - Somayyeh Shoorvazi
Y1  - 2013/04/02
PY  - 2013
N1  - https://doi.org/10.11648/j.bio.20130102.12
DO  - 10.11648/j.bio.20130102.12
T2  - American Journal of Bioscience and Bioengineering
JF  - American Journal of Bioscience and Bioengineering
JO  - American Journal of Bioscience and Bioengineering
SP  - 38
EP  - 42
PB  - Science Publishing Group
SN  - 2328-5893
UR  - https://doi.org/10.11648/j.bio.20130102.12
AB  - One of the most exciting subjects in science is the possibility of information loss in transcribing genetic se-quence of DNA into proteins due to acceleration of Universe. This research is the first attempt to investigate this subject. First, the probability that DNA is produced due to acceleration of Universe is obtained. It is found that as the Unruh tem-perature increases, the effect ofacceleration on the production of DNA becomes systematically more effective, because effect at higher temperatures, the energy that is supplied to keep Universe undergoing acceleration becomes more and consequently more DNAs are produced. Then the average number of binding proteins to DNA in two regions of Rindler space of Universe is calculated. The effect of proteins produced in region II doesn’t observe in accelerating Universe. One observer in acceleratingUniverse is unable to access information about the whole of space-time since, from his perspective, a communication horizon appears. This can result in a loss of information and a corresponding degradation ofprotein binding to DNA. This information loss disrupts the cellular dynamics and can lead to serious defects, including cancer.Next the averge number of extra base pairs that are produced in DNA structure by the acceleration of Universe is derived. These extra base pairs cause to be stored more information in DNA.These information can be transcribed of DNA into proteins and lead to dangerous activity in Human body.Finally,the probability for substituting AT pair by CG pair in DNA structure is calculated. It’s concluded that with increasing the Unruh temperature, more AT base pairs may be substituted by CG pairs and the probability for generating cancer due to this point mutation is increased.
VL  - 1
IS  - 2
ER  -

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Author Information

Alireza Sepehri

Faculty of Physics, Shahid Bahonar University, P.O. Box 76175, Kerman, Iran
Somayyeh Shoorvazi

Islamic Azad University , Neyshabur branch, Neyshabur, Iran

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Alireza Sepehri, Somayyeh Shoorvazi. (2013). The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. American Journal of Bioscience and Bioengineering, 1(2), 38-42. https://doi.org/10.11648/j.bio.20130102.12

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ACS Style

Alireza Sepehri; Somayyeh Shoorvazi. The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. Am. J. BioSci. Bioeng. 2013, 1(2), 38-42. doi: 10.11648/j.bio.20130102.12

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AMA Style

Alireza Sepehri, Somayyeh Shoorvazi. The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. Am J BioSci Bioeng. 2013;1(2):38-42. doi: 10.11648/j.bio.20130102.12

Copy | Download

@article{10.11648/j.bio.20130102.12,
  author = {Alireza Sepehri and Somayyeh Shoorvazi},
  title = {The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {1},
  number = {2},
  pages = {38-42},
  doi = {10.11648/j.bio.20130102.12},
  url = {https://doi.org/10.11648/j.bio.20130102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20130102.12},
  abstract = {One of the most exciting subjects in science is the possibility of information loss in transcribing genetic se-quence of DNA into proteins due to acceleration of Universe. This research is the first attempt to investigate this subject. First, the probability that DNA is produced due to acceleration of Universe is obtained. It is found that as the Unruh tem-perature increases, the effect ofacceleration on the production of DNA becomes systematically more effective, because effect at higher temperatures, the energy that is supplied to keep Universe undergoing acceleration becomes more and consequently more DNAs are produced. Then the average number of binding proteins to DNA in two regions of Rindler space of Universe is calculated. The effect of proteins produced in region II doesn’t observe in accelerating Universe. One observer in acceleratingUniverse is unable to access information about the whole of space-time since, from his perspective, a communication horizon appears. This can result in a loss of information and a corresponding degradation ofprotein binding to DNA. This information loss disrupts the cellular dynamics and can lead to serious defects, including cancer.Next the averge number of extra base pairs that are produced in DNA structure by the acceleration of Universe is derived. These extra base pairs cause to be stored more information in DNA.These information can be transcribed of DNA into proteins and lead to dangerous activity in Human body.Finally,the probability for substituting AT pair by CG pair in DNA structure is calculated. It’s concluded that with increasing the Unruh temperature, more AT base pairs may be substituted by CG pairs and the probability for generating cancer due to this point mutation is increased.},
 year = {2013}
}

Copy | Download

TY  - JOUR
T1  - The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe
AU  - Alireza Sepehri
AU  - Somayyeh Shoorvazi
Y1  - 2013/04/02
PY  - 2013
N1  - https://doi.org/10.11648/j.bio.20130102.12
DO  - 10.11648/j.bio.20130102.12
T2  - American Journal of Bioscience and Bioengineering
JF  - American Journal of Bioscience and Bioengineering
JO  - American Journal of Bioscience and Bioengineering
SP  - 38
EP  - 42
PB  - Science Publishing Group
SN  - 2328-5893
UR  - https://doi.org/10.11648/j.bio.20130102.12
AB  - One of the most exciting subjects in science is the possibility of information loss in transcribing genetic se-quence of DNA into proteins due to acceleration of Universe. This research is the first attempt to investigate this subject. First, the probability that DNA is produced due to acceleration of Universe is obtained. It is found that as the Unruh tem-perature increases, the effect ofacceleration on the production of DNA becomes systematically more effective, because effect at higher temperatures, the energy that is supplied to keep Universe undergoing acceleration becomes more and consequently more DNAs are produced. Then the average number of binding proteins to DNA in two regions of Rindler space of Universe is calculated. The effect of proteins produced in region II doesn’t observe in accelerating Universe. One observer in acceleratingUniverse is unable to access information about the whole of space-time since, from his perspective, a communication horizon appears. This can result in a loss of information and a corresponding degradation ofprotein binding to DNA. This information loss disrupts the cellular dynamics and can lead to serious defects, including cancer.Next the averge number of extra base pairs that are produced in DNA structure by the acceleration of Universe is derived. These extra base pairs cause to be stored more information in DNA.These information can be transcribed of DNA into proteins and lead to dangerous activity in Human body.Finally,the probability for substituting AT pair by CG pair in DNA structure is calculated. It’s concluded that with increasing the Unruh temperature, more AT base pairs may be substituted by CG pairs and the probability for generating cancer due to this point mutation is increased.
VL  - 1
IS  - 2
ER  -

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