A Review on Magnetic Microsphere

Satinder Kakar; Anurekha Jain

doi:doi:10.11648/j.ijbse.20170505.11

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A Review on Magnetic Microsphere

Satinder Kakar, Anurekha Jain

Published in International Journal of Biomedical Science and Engineering (Volume 5, Issue 5)

Received: 30 October 2017 Accepted: 29 November 2017 Published: 29 November 2017

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Abstract

Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 μm. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body.

Published in	International Journal of Biomedical Science and Engineering (Volume 5, Issue 5)
DOI	10.11648/j.ijbse.20170505.11
Page(s)	48-52
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Magnetic, Microspheres, Tissues

References

[1]	Divya Rathore, Satinder Kakar, Ramandeep Singh, “Microsheres–A Review” Innoriginal, 2016; 3(4): 12.
[2]	G. Poovi, S. Padmapriya, S. Lakshmi, “Review on Magnetic Microsphere”, Global Journal of Pharmacology 2015; 9 (4): 296.
[3]	Kakar Satinder, Singh Ramandeep, Batra Deepa. A review on target drug delivery: Magnetic microspheres. Journal of acute disease, 2013; 2(3): 189-195.
[4]	Mohamed K. Nasra, Moustafa M. Mohamed, Mohamed A. Elblbesy, Bothaina A. Hefney, “Preparation of Biocompatible Magnetic Microspheres with Chitosan”, Journal of Biomaterials and Nanobiotechnology, 2011: 2: 194-200.
[5]	Amol Chaudhari, K. R. Jadhav, Dr. Mr. V. J. Kadam, “An Over View: Microspheres as a nasal drug delivery system”, Journal of acute disease: 2010: 1-8.
[6]	Kakar Satinder, Singh Ramandeep, Batra Deepa. Preparation and evaluation of magnetic microspheres of 5-aminosalicyclic acid. Journal of acute disease, 2013; 2(3): 226-231.
[7]	Ramandeep Singh, Satinder Kakar, Charanjeet Kaur, “Magnetic Microspheres As A Boon Over Microspheres: A Review”, International Journal of Recent Advances in Pharmaceutical Research: 2015; 5(2): 68-74.
[8]	Ramteke K. H, Jadhav V. B, Dhole S. N., “Microspheres: as carrieres used for novel drug delivery system” IOSR Journal of Pharmacy (IOSRPHR). 2012; 2(4): 44-48.
[9]	Kakar Satinder, Singh Ramandeep, NautiyalUjjwal, Batra Deepa. Magnetic microspheres as magical novel drug delivery system: A Review. Journal of acute disease, 2013; 2(1): 1-12.
[10]	Sharina Abu Hanifah, Normah Hamzah & Lee Yook Heng, “Rapid Synthesis of Magnetic Microspheres Poly (Glycidyl Methacrylate-co-Styrene) by Photopolymerization”, Sains Malaysiana. 2013; 42(4): 487–493.
[11]	Tarun P, Soni S, Thakar B, Pandya V, Bharadia P, “Magnetic Microspheres as a Targeted Drug Delivery System: A Review”, International Journal for Pharmaceutical Research Scholars (IJPRS). 2012; 1(1): 12.
[12]	Satinder, K., Ramandeep, S. Preparation of magnetic microspheres of mesalamine by phase separation emulsion polymerization technique, Afr J Pharm Pharmacol, 2014; 8(9): 246-258.
[13]	Lei, Y. L., Liu, Z. Z., Liu, Q. F., Wu, X. Y. Synthesis of a macroporous hydrophilic ternary copolymer and its application in boronate-affinity separation, React Funct Polym, 2001; 48, 159–67.
[14]	W., Fricke, T., Riess, H., Brock, J. W., Huhn, D., Preclinical experiences with magnetic drug targeting: tolerance and efficacy, Cancer Res, 1996; 56(20), 4694–4701.

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Satinder Kakar, Anurekha Jain. (2017). A Review on Magnetic Microsphere. International Journal of Biomedical Science and Engineering, 5(5), 48-52. https://doi.org/10.11648/j.ijbse.20170505.11

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ACS Style

Satinder Kakar; Anurekha Jain. A Review on Magnetic Microsphere. Int. J. Biomed. Sci. Eng. 2017, 5(5), 48-52. doi: 10.11648/j.ijbse.20170505.11

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AMA Style

Satinder Kakar, Anurekha Jain. A Review on Magnetic Microsphere. Int J Biomed Sci Eng. 2017;5(5):48-52. doi: 10.11648/j.ijbse.20170505.11

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@article{10.11648/j.ijbse.20170505.11,
  author = {Satinder Kakar and Anurekha Jain},
  title = {A Review on Magnetic Microsphere},
  journal = {International Journal of Biomedical Science and Engineering},
  volume = {5},
  number = {5},
  pages = {48-52},
  doi = {10.11648/j.ijbse.20170505.11},
  url = {https://doi.org/10.11648/j.ijbse.20170505.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20170505.11},
  abstract = {Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 μm. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body.},
 year = {2017}
}

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TY  - JOUR
T1  - A Review on Magnetic Microsphere
AU  - Satinder Kakar
AU  - Anurekha Jain
Y1  - 2017/11/29
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbse.20170505.11
DO  - 10.11648/j.ijbse.20170505.11
T2  - International Journal of Biomedical Science and Engineering
JF  - International Journal of Biomedical Science and Engineering
JO  - International Journal of Biomedical Science and Engineering
SP  - 48
EP  - 52
PB  - Science Publishing Group
SN  - 2376-7235
UR  - https://doi.org/10.11648/j.ijbse.20170505.11
AB  - Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 μm. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body.
VL  - 5
IS  - 5
ER  -

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Author Information

Satinder Kakar

Department of Pharmacy, Jayoti Vidyapeeth Women’s University, Jaipur, Rajasthan, India
Anurekha Jain

Department of Pharmacy, Jayoti Vidyapeeth Women’s University, Jaipur, Rajasthan, India

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APA Style

Satinder Kakar, Anurekha Jain. (2017). A Review on Magnetic Microsphere. International Journal of Biomedical Science and Engineering, 5(5), 48-52. https://doi.org/10.11648/j.ijbse.20170505.11

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ACS Style

Satinder Kakar; Anurekha Jain. A Review on Magnetic Microsphere. Int. J. Biomed. Sci. Eng. 2017, 5(5), 48-52. doi: 10.11648/j.ijbse.20170505.11

Copy | Download

AMA Style

Satinder Kakar, Anurekha Jain. A Review on Magnetic Microsphere. Int J Biomed Sci Eng. 2017;5(5):48-52. doi: 10.11648/j.ijbse.20170505.11

Copy | Download

@article{10.11648/j.ijbse.20170505.11,
  author = {Satinder Kakar and Anurekha Jain},
  title = {A Review on Magnetic Microsphere},
  journal = {International Journal of Biomedical Science and Engineering},
  volume = {5},
  number = {5},
  pages = {48-52},
  doi = {10.11648/j.ijbse.20170505.11},
  url = {https://doi.org/10.11648/j.ijbse.20170505.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20170505.11},
  abstract = {Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 μm. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - A Review on Magnetic Microsphere
AU  - Satinder Kakar
AU  - Anurekha Jain
Y1  - 2017/11/29
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbse.20170505.11
DO  - 10.11648/j.ijbse.20170505.11
T2  - International Journal of Biomedical Science and Engineering
JF  - International Journal of Biomedical Science and Engineering
JO  - International Journal of Biomedical Science and Engineering
SP  - 48
EP  - 52
PB  - Science Publishing Group
SN  - 2376-7235
UR  - https://doi.org/10.11648/j.ijbse.20170505.11
AB  - Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and ideally having a particle size less than 200 μm. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a given drug. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. One such approach is using microspheres as carriers for drugs. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. In future by combining various other strategies, microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body.
VL  - 5
IS  - 5
ER  -

Copy | Download