Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA

Lheureux Helene; Randriamahazo Rakotomalala Toky; Mons Joffrey; Gabriele Marc

doi:doi:10.11648/j.iji.20170503.12

| Peer-Reviewed

Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA

Lheureux Helene, Randriamahazo Rakotomalala Toky, Mons Joffrey, Gabriele Marc

Published in International Journal of Immunology (Volume 5, Issue 3)

Received: 31 May 2017 Accepted: 12 June 2017 Published: 17 July 2017

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Anti-sperm antibodies (ASA) form a class of glycoproteins commonly found in infertile men. This class of antibody causes an impairment of the spermatozoon's ability to cross cervical mucus and interact with the oocyte. The aim of our study was to analyze clinical and biological parameters of the sperm among positive ASA patients seen at the Center of Assisted Medical Procreation of the CHU Reunion before and after in-vitro treatment of autoimmune sperms. During the period from April 01, 2013 to February 29, 2015, we analyzed clinico-biological parameters of patients coming for exploring an infertility state with ASA IgG and IgA research before and after sperm treatment. Fourteen (1.51%) patients had a positive ASA, with a combination of ASA IgG and IgA for 71.42% of them. After in vitro treatment of the autoimmune sperm we found a persistence of IgA in 21.43% without IgG.

Published in	International Journal of Immunology (Volume 5, Issue 3)
DOI	10.11648/j.iji.20170503.12
Page(s)	49-52
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Anti-Sperm Antibodies, Sperm Treatment, Réunion Island

References

[1]	World Health Organization. World Health Organization manualfor the standardised investigation and diagnosis of the infertilecouple. Cambridge: Cambridge University Press; 2000.
[2]	Nakabayashi, N. T., Tyler, E. T., & Tyler, A. (1961). Immunologic aspects of human infertility. Fertility and sterility, 12(6), 544-50.
[3]	Meinertz H, Linnet L, Fogh-Andersen P, et al. Antisperm anti-bodies and fertility after vasovasostomy: a follow-up study of216 men. FertilSteril 1990; 54: 315—21.
[4]	World Health Organization. WHO Laboratory Manual for the Examination and Processing of Human Semen, 5th ed. Geneva 2010.
[5]	Blanc B, Boubli L. Infertilité du couple. Gynécologie. Paris: ÉditionPradel; 2003.
[6]	Merzndar S, Levine S. Antisperm antibodies: etiology, pathogenesis, diagnosis and treatment. FertilSteril 1998; 70: 799—810.
[7]	Marconi M, Nowotny A, Pantke P. Antisperm antibodies detec-ted by mixed agglutination reaction and immunobead test arenot associated with chronic inflammation and infection of semi-nal tract. Andrology 2008; 40: 227—34.
[8]	Wolff H, Polich JA, Martinez A, Haimovici F, Hill JA, AndersonDJ. Leukocytospermia is associated with poor semen quality. FertilSteril 1990; 53: 528—36.
[9]	Lenzi, et al. Unilateral cryptorchidism corrected in prepubertalage: evaluation of sperm parameters, hormones and antispermantibodies in adult age. FertilSteril 1997; 5: 943—8.
[10]	Gilbert BR, Witkim SS, Goldstein M. Correlation of sperm-boundimmunoglobulins with impaired semen analysis in infertile menwithvaricoceles. Fertil Steril 1989; 52: 469—73.
[11]	Barthélémy C. Indications de la recherche des anticorps anti-spermatozoïdes. Andrologie 2003; 13(1): 70—80.
[12]	De Muylder X, et al. La stérilité d’origine immunologique. CanMed Assoc J 2002; 130: 591—602.
[13]	Jager S, Kremer J, Kuiken J, Mulder I. The significance ofthe Fc part of anti spermatozoal antibodies for the shaking.
[14]	Meinertz H, Linnet L, Fogh-Andersen P, et al. Antisperm anti-bodies and fertility after vasovasostomy: a follow-up study of216 men. FertilSteril 1990; 54: 315—21.
[15]	Check JH, Hourani W, Check ML, Graziano V, Levin E. Effectof treating antibody-coated sperm with chymotrypsin on pre-gnancy rates following IUI as compared to outcome of IVF/ICSI. ArchAndrol 2004; 50: 93—5.
[16]	Ombelet W, Vandeput H, Janssen M, Cox A, Vossen C, PolletH, et al. Treatment of male infertility due to sperm surfaceantibodies: IUI or IVF? Hum Reprod 1997; 12(6): 1167—70.
[17]	Naggy, et al. Results of 55 intracytoplasmic sperm injectioncycles in the treatment of male immunological infertility. HumReprod 1995; 10: 1775—80.
[18]	Mahmoud A, Comhaire F. Antisperm antibodies: use of themixed agglutination reaction (MAR) test using latex beads. HumReprod 2000; 15: 231—3.
[19]	Francavilla F et al. (1992): Failure of intrauterine insemination in male immunological infertility in cases which all spermatozoa are antibody-coated. FertilSteril 58: 587–592.
[20]	Hjort T, Meinertz H (1988) Antisperm antibodies and immune subfertility. Hum Reprod3, 59-67.

Cite This Article

Plain Text BibTeX RIS

APA Style

Lheureux Helene, Randriamahazo Rakotomalala Toky, Mons Joffrey, Gabriele Marc. (2017). Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA. International Journal of Immunology, 5(3), 49-52. https://doi.org/10.11648/j.iji.20170503.12

Copy | Download

ACS Style

Lheureux Helene; Randriamahazo Rakotomalala Toky; Mons Joffrey; Gabriele Marc. Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA. Int. J. Immunol. 2017, 5(3), 49-52. doi: 10.11648/j.iji.20170503.12

Copy | Download

AMA Style

Lheureux Helene, Randriamahazo Rakotomalala Toky, Mons Joffrey, Gabriele Marc. Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA. Int J Immunol. 2017;5(3):49-52. doi: 10.11648/j.iji.20170503.12

Copy | Download

@article{10.11648/j.iji.20170503.12,
  author = {Lheureux Helene and Randriamahazo Rakotomalala Toky and Mons Joffrey and Gabriele Marc},
  title = {Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA},
  journal = {International Journal of Immunology},
  volume = {5},
  number = {3},
  pages = {49-52},
  doi = {10.11648/j.iji.20170503.12},
  url = {https://doi.org/10.11648/j.iji.20170503.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20170503.12},
  abstract = {Anti-sperm antibodies (ASA) form a class of glycoproteins commonly found in infertile men. This class of antibody causes an impairment of the spermatozoon's ability to cross cervical mucus and interact with the oocyte. The aim of our study was to analyze clinical and biological parameters of the sperm among positive ASA patients seen at the Center of Assisted Medical Procreation of the CHU Reunion before and after in-vitro treatment of autoimmune sperms. During the period from April 01, 2013 to February 29, 2015, we analyzed clinico-biological parameters of patients coming for exploring an infertility state with ASA IgG and IgA research before and after sperm treatment. Fourteen (1.51%) patients had a positive ASA, with a combination of ASA IgG and IgA for 71.42% of them. After in vitro treatment of the autoimmune sperm we found a persistence of IgA in 21.43% without IgG.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA
AU  - Lheureux Helene
AU  - Randriamahazo Rakotomalala Toky
AU  - Mons Joffrey
AU  - Gabriele Marc
Y1  - 2017/07/17
PY  - 2017
N1  - https://doi.org/10.11648/j.iji.20170503.12
DO  - 10.11648/j.iji.20170503.12
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 49
EP  - 52
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20170503.12
AB  - Anti-sperm antibodies (ASA) form a class of glycoproteins commonly found in infertile men. This class of antibody causes an impairment of the spermatozoon's ability to cross cervical mucus and interact with the oocyte. The aim of our study was to analyze clinical and biological parameters of the sperm among positive ASA patients seen at the Center of Assisted Medical Procreation of the CHU Reunion before and after in-vitro treatment of autoimmune sperms. During the period from April 01, 2013 to February 29, 2015, we analyzed clinico-biological parameters of patients coming for exploring an infertility state with ASA IgG and IgA research before and after sperm treatment. Fourteen (1.51%) patients had a positive ASA, with a combination of ASA IgG and IgA for 71.42% of them. After in vitro treatment of the autoimmune sperm we found a persistence of IgA in 21.43% without IgG.
VL  - 5
IS  - 3
ER  -

Copy | Download

Author Information

Lheureux Helene

Assisted Medical Procreation Center, University Center Hospital South Réunion, Réunion Island, France
Randriamahazo Rakotomalala Toky

Assisted Medical Procreation Center, University Center Hospital South Réunion, Réunion Island, France
Mons Joffrey

Assisted Medical Procreation Center, University Center Hospital South Réunion, Réunion Island, France
Gabriele Marc

Assisted Medical Procreation Center, University Center Hospital South Réunion, Réunion Island, France

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Lheureux Helene, Randriamahazo Rakotomalala Toky, Mons Joffrey, Gabriele Marc. (2017). Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA. International Journal of Immunology, 5(3), 49-52. https://doi.org/10.11648/j.iji.20170503.12

Copy | Download

ACS Style

Lheureux Helene; Randriamahazo Rakotomalala Toky; Mons Joffrey; Gabriele Marc. Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA. Int. J. Immunol. 2017, 5(3), 49-52. doi: 10.11648/j.iji.20170503.12

Copy | Download

AMA Style

Lheureux Helene, Randriamahazo Rakotomalala Toky, Mons Joffrey, Gabriele Marc. Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA. Int J Immunol. 2017;5(3):49-52. doi: 10.11648/j.iji.20170503.12

Copy | Download

@article{10.11648/j.iji.20170503.12,
  author = {Lheureux Helene and Randriamahazo Rakotomalala Toky and Mons Joffrey and Gabriele Marc},
  title = {Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA},
  journal = {International Journal of Immunology},
  volume = {5},
  number = {3},
  pages = {49-52},
  doi = {10.11648/j.iji.20170503.12},
  url = {https://doi.org/10.11648/j.iji.20170503.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20170503.12},
  abstract = {Anti-sperm antibodies (ASA) form a class of glycoproteins commonly found in infertile men. This class of antibody causes an impairment of the spermatozoon's ability to cross cervical mucus and interact with the oocyte. The aim of our study was to analyze clinical and biological parameters of the sperm among positive ASA patients seen at the Center of Assisted Medical Procreation of the CHU Reunion before and after in-vitro treatment of autoimmune sperms. During the period from April 01, 2013 to February 29, 2015, we analyzed clinico-biological parameters of patients coming for exploring an infertility state with ASA IgG and IgA research before and after sperm treatment. Fourteen (1.51%) patients had a positive ASA, with a combination of ASA IgG and IgA for 71.42% of them. After in vitro treatment of the autoimmune sperm we found a persistence of IgA in 21.43% without IgG.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Effects of Sperm Treatment on the Anti-sperm Antibodies IgG and IgA
AU  - Lheureux Helene
AU  - Randriamahazo Rakotomalala Toky
AU  - Mons Joffrey
AU  - Gabriele Marc
Y1  - 2017/07/17
PY  - 2017
N1  - https://doi.org/10.11648/j.iji.20170503.12
DO  - 10.11648/j.iji.20170503.12
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 49
EP  - 52
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20170503.12
AB  - Anti-sperm antibodies (ASA) form a class of glycoproteins commonly found in infertile men. This class of antibody causes an impairment of the spermatozoon's ability to cross cervical mucus and interact with the oocyte. The aim of our study was to analyze clinical and biological parameters of the sperm among positive ASA patients seen at the Center of Assisted Medical Procreation of the CHU Reunion before and after in-vitro treatment of autoimmune sperms. During the period from April 01, 2013 to February 29, 2015, we analyzed clinico-biological parameters of patients coming for exploring an infertility state with ASA IgG and IgA research before and after sperm treatment. Fourteen (1.51%) patients had a positive ASA, with a combination of ASA IgG and IgA for 71.42% of them. After in vitro treatment of the autoimmune sperm we found a persistence of IgA in 21.43% without IgG.
VL  - 5
IS  - 3
ER  -

Copy | Download