The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents

Iliya Mikhailovich Strekalov; Leonid Petrovich Larionov; Мikhail Georgievich Zuev; Elena Yuryevna Zhuravleva

doi:doi:10.11648/j.ijmi.20160403.12

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The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents

Iliya Mikhailovich Strekalov, Leonid Petrovich Larionov, Мikhail Georgievich Zuev, Elena Yuryevna Zhuravleva

Published in International Journal of Medical Imaging (Volume 4, Issue 3)

Received: 16 June 2016 Accepted: 5 July 2016 Published: 18 July 2016

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Abstract

It is known that there is a high risk of progression of side effects in kidneys, so-called nephropathy induced with X-ray contrast agents, at applying of water-soluble X-ray contrast agents in medical practice. New water-insoluble compounds of orthotantalates of rare-earth elements are offered as new X-ray contrast agents for endocavitary administration. The achieved results have shown the absence of general toxic effect on bodies of animals, high X-ray contrast properties in vitro and in vivo experiments. The investigations were performed on white nondescript mice, rats Wistar subtype and Chinchilla rabbits.

Published in	International Journal of Medical Imaging (Volume 4, Issue 3)
DOI	10.11648/j.ijmi.20160403.12
Page(s)	17-22
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

X-ray Contract Agents, Nephropathy Induced with X-ray Contrast Agents, Orthotantalates of Rare-Earth Elements

References

[1]	Rosenstrauch L. S. Prevention of complications in X-ray studies with the use of contrast agents / L. S. Rosenstrauch // Vestnik rentgenologii i radiologii. 1978. No. 9, pp. 31 – 35. [in Russian].
[2]	Shimanovskii N. L. Contrast agents. Efficient application guide. Moscow: GEOTAR–Media. 2009. 463 p. [in Russian].
[3]	John A. K. Renal insufficiency: gadopentetate dimeglumine as a radiographic contrast agent during peripheral vascular interventional procedures / A. K. John, C. G. Stuart, C. W. Arthur // Radiology. 1996. Vol. 198, pp. 579 – 581.
[4]	Gomes A. S. Acute renal dysfunction in high–risk patients after angiography: comparison of ionic contrast media / A. S. Gomes, I. F. Lois, I. D. Baxer // Radiology. 1989. Vol. 121, No. 14, pp. 410 – 415.
[5]	Sergeyev P. V., Sviridov N. K., Shimanovskii N. L. X-ray contrast agents. Moscow: Meditsina. 1993. 307 p. [in Russian].
[6]	Strekalov I. M. A new X-ray contrast agent – lanthanum orthotantalate and possibilities of its application in abdominal surgery (experimental study): candidate of science (medicine) thesis / I. M. Strekalov / Ekaterinburg. 2007, pp. 84 – 87. [in Russian].
[7]	Velmas T. / Gd–DTPA as an alternative contrast agent in conventional and interventional and radiology / T. Velmas T. Markkola // Acta Radiol. 1998. Vol. 39, pp. 223 – 226.
[8]	Zuev M. G., Larionov L. P. Tantalum X-ray contrast agents (Solid-State Chemistry for Medicine Series). Ekaterinburg: Ural. Otd., Ross. Akad. Nauk, 2002. ISBN 5-7691-1282-4. [in Russian]. 155 p.
[9]	New Materials for Medicine / Collective of authors, M. G. Zuev and L. P. Larionov, Eds., Eekaterinburg: Ural. Otd., Ross. Akad. Nauk, 2006. ISBN 5-7691-1718-4. [in Russian]. 166 p.
[10]	Zhuravleva E. Yu. Tantalum X-ray Contrast Media (Solid-State Chemistry for Medicine Series), by M. G. Zuev and L. P. Larionov, Eekaterinburg: Ural. Otd., Ross. Akad. Nauk, 2002 // Inorganic Materials, Vol. 40, No. 6, 2004, pp. 671 – 672.
[11]	Zhuravleva E. Yu. New Materials for Medicine, M. G. Zuev and L. P. Larionov, Eds., Eekaterinburg: Ural. Otd., Ross. Akad. Nauk, 2006 // Inorganic Materials, 2007, Vol. 43, No. 9, p. 1034.
[12]	Zuev M. G. and Larionov L. P. "Tantalic Radio-Opaque Drugs. Preclinical Studies" Monography. Lambert Academic Publishing, 2012. 250 p. [in Russian].
[13]	Strekalov I. M., Larionov L. P., Zuyev M. G. // Vestnik rentgenologii i radiologii. 2007 NO 1, pp. 45 – 54.

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Iliya Mikhailovich Strekalov, Leonid Petrovich Larionov, Мikhail Georgievich Zuev, Elena Yuryevna Zhuravleva. (2016). The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents. International Journal of Medical Imaging, 4(3), 17-22. https://doi.org/10.11648/j.ijmi.20160403.12

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ACS Style

Iliya Mikhailovich Strekalov; Leonid Petrovich Larionov; Мikhail Georgievich Zuev; Elena Yuryevna Zhuravleva. The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents. Int. J. Med. Imaging 2016, 4(3), 17-22. doi: 10.11648/j.ijmi.20160403.12

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AMA Style

Iliya Mikhailovich Strekalov, Leonid Petrovich Larionov, Мikhail Georgievich Zuev, Elena Yuryevna Zhuravleva. The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents. Int J Med Imaging. 2016;4(3):17-22. doi: 10.11648/j.ijmi.20160403.12

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@article{10.11648/j.ijmi.20160403.12,
  author = {Iliya Mikhailovich Strekalov and Leonid Petrovich Larionov and Мikhail Georgievich Zuev and Elena Yuryevna Zhuravleva},
  title = {The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents},
  journal = {International Journal of Medical Imaging},
  volume = {4},
  number = {3},
  pages = {17-22},
  doi = {10.11648/j.ijmi.20160403.12},
  url = {https://doi.org/10.11648/j.ijmi.20160403.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20160403.12},
  abstract = {It is known that there is a high risk of progression of side effects in kidneys, so-called nephropathy induced with X-ray contrast agents, at applying of water-soluble X-ray contrast agents in medical practice. New water-insoluble compounds of orthotantalates of rare-earth elements are offered as new X-ray contrast agents for endocavitary administration. The achieved results have shown the absence of general toxic effect on bodies of animals, high X-ray contrast properties in vitro and in vivo experiments. The investigations were performed on white nondescript mice, rats Wistar subtype and Chinchilla rabbits.},
 year = {2016}
}

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TY  - JOUR
T1  - The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents
AU  - Iliya Mikhailovich Strekalov
AU  - Leonid Petrovich Larionov
AU  - Мikhail Georgievich Zuev
AU  - Elena Yuryevna Zhuravleva
Y1  - 2016/07/18
PY  - 2016
N1  - https://doi.org/10.11648/j.ijmi.20160403.12
DO  - 10.11648/j.ijmi.20160403.12
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 17
EP  - 22
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20160403.12
AB  - It is known that there is a high risk of progression of side effects in kidneys, so-called nephropathy induced with X-ray contrast agents, at applying of water-soluble X-ray contrast agents in medical practice. New water-insoluble compounds of orthotantalates of rare-earth elements are offered as new X-ray contrast agents for endocavitary administration. The achieved results have shown the absence of general toxic effect on bodies of animals, high X-ray contrast properties in vitro and in vivo experiments. The investigations were performed on white nondescript mice, rats Wistar subtype and Chinchilla rabbits.
VL  - 4
IS  - 3
ER  -

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Author Information

Iliya Mikhailovich Strekalov

Central City Clinical Hospital No. 1, Ekaterinburg, Russia
Leonid Petrovich Larionov

Department of Pharmacology and Clinical Pharmacology, Faculty of Pharmacy, Ural State Medical University, Ekaterinburg, Russia
Мikhail Georgievich Zuev

Oxide Systems Laboratory, Institute of Solid State Chemistry, Ural Branch of Russian Academy of Sciences, Ekaterinburg, Russia
Elena Yuryevna Zhuravleva

Experimental Physics Department, Physico-Technical Institute, Ural Federal University Named After the First President of Russia B. N. Yeltsin, Ekaterinburg, Russia

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APA Style

Iliya Mikhailovich Strekalov, Leonid Petrovich Larionov, Мikhail Georgievich Zuev, Elena Yuryevna Zhuravleva. (2016). The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents. International Journal of Medical Imaging, 4(3), 17-22. https://doi.org/10.11648/j.ijmi.20160403.12

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ACS Style

Iliya Mikhailovich Strekalov; Leonid Petrovich Larionov; Мikhail Georgievich Zuev; Elena Yuryevna Zhuravleva. The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents. Int. J. Med. Imaging 2016, 4(3), 17-22. doi: 10.11648/j.ijmi.20160403.12

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AMA Style

Iliya Mikhailovich Strekalov, Leonid Petrovich Larionov, Мikhail Georgievich Zuev, Elena Yuryevna Zhuravleva. The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents. Int J Med Imaging. 2016;4(3):17-22. doi: 10.11648/j.ijmi.20160403.12

Copy | Download

@article{10.11648/j.ijmi.20160403.12,
  author = {Iliya Mikhailovich Strekalov and Leonid Petrovich Larionov and Мikhail Georgievich Zuev and Elena Yuryevna Zhuravleva},
  title = {The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents},
  journal = {International Journal of Medical Imaging},
  volume = {4},
  number = {3},
  pages = {17-22},
  doi = {10.11648/j.ijmi.20160403.12},
  url = {https://doi.org/10.11648/j.ijmi.20160403.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20160403.12},
  abstract = {It is known that there is a high risk of progression of side effects in kidneys, so-called nephropathy induced with X-ray contrast agents, at applying of water-soluble X-ray contrast agents in medical practice. New water-insoluble compounds of orthotantalates of rare-earth elements are offered as new X-ray contrast agents for endocavitary administration. The achieved results have shown the absence of general toxic effect on bodies of animals, high X-ray contrast properties in vitro and in vivo experiments. The investigations were performed on white nondescript mice, rats Wistar subtype and Chinchilla rabbits.},
 year = {2016}
}

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TY  - JOUR
T1  - The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents
AU  - Iliya Mikhailovich Strekalov
AU  - Leonid Petrovich Larionov
AU  - Мikhail Georgievich Zuev
AU  - Elena Yuryevna Zhuravleva
Y1  - 2016/07/18
PY  - 2016
N1  - https://doi.org/10.11648/j.ijmi.20160403.12
DO  - 10.11648/j.ijmi.20160403.12
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 17
EP  - 22
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20160403.12
AB  - It is known that there is a high risk of progression of side effects in kidneys, so-called nephropathy induced with X-ray contrast agents, at applying of water-soluble X-ray contrast agents in medical practice. New water-insoluble compounds of orthotantalates of rare-earth elements are offered as new X-ray contrast agents for endocavitary administration. The achieved results have shown the absence of general toxic effect on bodies of animals, high X-ray contrast properties in vitro and in vivo experiments. The investigations were performed on white nondescript mice, rats Wistar subtype and Chinchilla rabbits.
VL  - 4
IS  - 3
ER  -

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