Hemoglobin S is a hereditary blood pathology, with higher prevalence worldwide. The homozygous patients have anemia in varying degrees of severity, while heterozygous carrier sickle cell trait may have hematocrit and hemoglobin which can be used in donation. The hemoglobin carrier erythrocyte characteristics does not allow you to be a good donor blood transfusion undesirable effects may be due to both the potential sickling as to changes in hemotherapeutic product as a result of processing and storage. In Cape Verde, no studies related to the prevalence of hemoglobin S and program for screening of hemoglobin S in the blood donors are reported. The main objective of this study was to determine the prevalence of hemoglobin S in blood donors attended in the Dr. Agostinho Neto Hospital, between August to October (2013). Sickling of red blood cell technique was performed. Between samples we found that four donors from 104 (3.9%) that were screened had positive results, gender, age and hemoglobin concentration, naturally, county of residence, blood groups and regular donors were associated with the presence of such a hemoglobin variant. The results underscore the importance of screening this abnormality in the blood donors and further studies must be performed. Also we recommend the implementation of information strategies, awareness, early detection and treatment of diseases associated with hemoglobin S.
| Published in | Science Journal of Public Health (Volume 3, Issue 5) |
| DOI | 10.11648/j.sjph.20150305.11 |
| Page(s) | 600-604 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Cape Verde, Blood Donation, Hemoglobin S, Prevalence
| [1] | Aguiar, K. M., Maia, C.N. (2011). Prevalence of hemoglobin S in blood donors at the Hemocentro Regional in the Town of Montes Claros, Minas Gerais. RBAC. 43(4): 284-287. |
| [2] | Alves, J. B. (2010). Malaria epidemiology in Cape Verde - Human Genetic factors and population structure of the mosquito vector. Institute of Hygiene and Tropical Medicine, Master's thesis, University Nova de Lisboa: 205p. |
| [3] | Cruz, J. M., Brandão, C., Barreira, M.J., Amorim, A & Rebimbas, M.C. (1979). Genetic Studies in Cape Verde Archipelago (hemoglobin, haptoglobin and ABO and MN blood groups). 36: 9p. |
| [4] | Grignani C, A. C., Iamamoto C, Gonçalves T, Mashima D et al. (2006). Prevalence of hemoglobin AS among blood donors from Londrina - Paraná.RBAC. 38(4): (259-62). |
| [5] | Hicks, E. J., Griep, J. A., Nordschow, C., D. (1973). Comparison of Results for Three Methods of Hemoglobin S Identification. Clin. Chem. 19/5: p. 533-535. |
| [6] | Lisot, C. L. A. (2003). Screening of hemoglobinopathies in blood donors in Italian colonization area of Rio Grande do Sul, Brasil.School medicine Dissertation. University Federal do Rio Grande do Sul.: 144p. |
| [7] | Marques, J. R. (1994). Transfusion of red blood cells containing hemoglobin S.BolSoc Bras HematolHemoter. XVI (166): 229-232. |
| [8] | Murao, M., Ferraz, M.H.C. (2007). Sickle cell trait - heterozygosity for hemoglobin S. Rev. bras. hematol. hemoter. 29(3): 223-225. |
| [9] | Naoum, P. C., Naoum, F.A. (2004). Sickle cell disease. S. P. Sarvier. |
| [10] | Oshiro, M., Neto, A.P., MighitaM, K., Watanabe, C.I., Palharin,i D.L.B. (1999). Comparative study of solubility tests, sickling and gel-centrifugation for population detection of hemoglobin S. Journal.InstAdolfo Lutz. 58: 53-56. |
| [11] | Paiva, E., Silva, R.B., Ramalho, A.S. (1997). Risks and benefits of genetic screening: the sickle cell trait as a model in a Brazilian population. Book. Health Public. 13(2): 285-294. |
| [12] | Rodrigues, A. S. N., Nascimento, R.E., Castelo, N.M. (2012). Sickle cell trait: the impact on public health. Equatorial Science. v, 2 - Nº 2.ISSN 2179-9563: 6p. |
| [13] | Naoum, P. Prevalence and control of hemoglobin S. Rev. Bras. Hematol. Hemoter., 22 (2):142-148. |
| [14] | Varela, E. M. M. (2011). Predisposing factors for membership to blood donation among students at the University of Cape Verde - Campus Palmarejo. Department of Science and Technology. Thesis, University of Cape Verde: 68p. |
| [15] | Freire, A. J. C. (2012). Serologic profile of blood donors from Santiago North Health Region from 2008 to 2011. Department of Science and Technology. Thesis, University of Cape Verde: 80p. |
| [16] | Rodrigues, ASN, Nascimento, RE, Castle, NM (2012). Sickle cell trait: the impact on public health. Equatorial science. v,2 - Number 2.ISSN 2179-9563: 6p. |
| [17] | WHO Working Group. (1982). Hereditary anemia. genetics basic, clinical features, diagnosis and treatment. WHO, 60: 643-60. |
APA Style
Leonel Barbosa Gonçalves, Elves Heleno Gomes Duarte, Marilena Djata Cabral. (2015). Prevalence of Hemoglobin S in Blood Donors in the Hospital Dr. Agostinho Neto, Praia City – Cape Verde. Science Journal of Public Health, 3(5), 600-604. https://doi.org/10.11648/j.sjph.20150305.11
ACS Style
Leonel Barbosa Gonçalves; Elves Heleno Gomes Duarte; Marilena Djata Cabral. Prevalence of Hemoglobin S in Blood Donors in the Hospital Dr. Agostinho Neto, Praia City – Cape Verde. Sci. J. Public Health 2015, 3(5), 600-604. doi: 10.11648/j.sjph.20150305.11
AMA Style
Leonel Barbosa Gonçalves, Elves Heleno Gomes Duarte, Marilena Djata Cabral. Prevalence of Hemoglobin S in Blood Donors in the Hospital Dr. Agostinho Neto, Praia City – Cape Verde. Sci J Public Health. 2015;3(5):600-604. doi: 10.11648/j.sjph.20150305.11
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Download@article{10.11648/j.sjph.20150305.11,
author = {Leonel Barbosa Gonçalves and Elves Heleno Gomes Duarte and Marilena Djata Cabral},
title = {Prevalence of Hemoglobin S in Blood Donors in the Hospital Dr. Agostinho Neto, Praia City – Cape Verde},
journal = {Science Journal of Public Health},
volume = {3},
number = {5},
pages = {600-604},
doi = {10.11648/j.sjph.20150305.11},
url = {https://doi.org/10.11648/j.sjph.20150305.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20150305.11},
abstract = {Hemoglobin S is a hereditary blood pathology, with higher prevalence worldwide. The homozygous patients have anemia in varying degrees of severity, while heterozygous carrier sickle cell trait may have hematocrit and hemoglobin which can be used in donation. The hemoglobin carrier erythrocyte characteristics does not allow you to be a good donor blood transfusion undesirable effects may be due to both the potential sickling as to changes in hemotherapeutic product as a result of processing and storage. In Cape Verde, no studies related to the prevalence of hemoglobin S and program for screening of hemoglobin S in the blood donors are reported. The main objective of this study was to determine the prevalence of hemoglobin S in blood donors attended in the Dr. Agostinho Neto Hospital, between August to October (2013). Sickling of red blood cell technique was performed. Between samples we found that four donors from 104 (3.9%) that were screened had positive results, gender, age and hemoglobin concentration, naturally, county of residence, blood groups and regular donors were associated with the presence of such a hemoglobin variant. The results underscore the importance of screening this abnormality in the blood donors and further studies must be performed. Also we recommend the implementation of information strategies, awareness, early detection and treatment of diseases associated with hemoglobin S.},
year = {2015}
}
TY - JOUR T1 - Prevalence of Hemoglobin S in Blood Donors in the Hospital Dr. Agostinho Neto, Praia City – Cape Verde AU - Leonel Barbosa Gonçalves AU - Elves Heleno Gomes Duarte AU - Marilena Djata Cabral Y1 - 2015/06/17 PY - 2015 N1 - https://doi.org/10.11648/j.sjph.20150305.11 DO - 10.11648/j.sjph.20150305.11 T2 - Science Journal of Public Health JF - Science Journal of Public Health JO - Science Journal of Public Health SP - 600 EP - 604 PB - Science Publishing Group SN - 2328-7950 UR - https://doi.org/10.11648/j.sjph.20150305.11 AB - Hemoglobin S is a hereditary blood pathology, with higher prevalence worldwide. The homozygous patients have anemia in varying degrees of severity, while heterozygous carrier sickle cell trait may have hematocrit and hemoglobin which can be used in donation. The hemoglobin carrier erythrocyte characteristics does not allow you to be a good donor blood transfusion undesirable effects may be due to both the potential sickling as to changes in hemotherapeutic product as a result of processing and storage. In Cape Verde, no studies related to the prevalence of hemoglobin S and program for screening of hemoglobin S in the blood donors are reported. The main objective of this study was to determine the prevalence of hemoglobin S in blood donors attended in the Dr. Agostinho Neto Hospital, between August to October (2013). Sickling of red blood cell technique was performed. Between samples we found that four donors from 104 (3.9%) that were screened had positive results, gender, age and hemoglobin concentration, naturally, county of residence, blood groups and regular donors were associated with the presence of such a hemoglobin variant. The results underscore the importance of screening this abnormality in the blood donors and further studies must be performed. Also we recommend the implementation of information strategies, awareness, early detection and treatment of diseases associated with hemoglobin S. VL - 3 IS - 5 ER -
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